SCHEMBL9889352

SCHEMBL9889352

CCN1CCN(P(=O)(O)O)C1=N

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
INMT O95050 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984828 0.78 CYP2D6 (0.36)
SCHEMBL11982462 0.73 INMT (0.43) INMT
SCHEMBL14344950 0.66
SCHEMBL329869 0.59 F2 (0.45) INMT
Phosphoric Acid SCHEMBL30540294 0.58
SCHEMBL19379300 0.58 BRD4 (0.30)
SCHEMBL11759308 0.56 POLB (0.40)
SCHEMBL9815040 0.56 L3MBTL1 (0.40) INMT
SCHEMBL24052062 0.54 INMT (0.31) INMT
SCHEMBL8740911 0.54 INMT (0.33) INMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION WASHINGTON UNIVERSITY 2023-09-14 US disclosed
US-20210393563-A1 METHODS FOR TREATING MICROGLIAL DYSFUNCTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-12-23 US disclosed
US-9434753-B2 Modified creatine compounds GENCIA CORPORATION (US) 2016-09-06 US disclosed
US-20150005258-A1 Modified Creatine Compounds Genci Corporation (US) 2015-01-01 US disclosed
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF GENCIA CORPORATION (US) 2014-02-13 US disclosed
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof GENCIA CORPORATION (US) 2013-03-21 US disclosed
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2012-06-07 US disclosed
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-04-14 US disclosed
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-01-27 US disclosed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US disclosed
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF CS, UQCRC1, UQCRC2 INMT 2619/4885
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20210393563-A1 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CHRNB2, PSEN2, CX3CR1 INMT 2643/4885
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CX3CR1, CD68, FYN INMT 2721/4885
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof UQCRC1, CS, UQCRC2 INMT 2820/4885
US-20150005258-A1 Modified Creatine Compounds CKMT1A; CKMT1B, SLC25A20, ARG2 INMT 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.