SCHEMBL9889352

SCHEMBL9889352

CCN1CCN(P(=O)(O)O)C1=N

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ INMT O95050 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1984828 0.78 CYP2D6 (0.36) —
SCHEMBL11982462 0.73 INMT (0.43) INMT
SCHEMBL14344950 0.66 — —
SCHEMBL329869 0.59 F2 (0.45) INMT
Phosphoric Acid SCHEMBL30540294 0.58 — —
SCHEMBL19379300 0.58 BRD4 (0.30) —
SCHEMBL11759308 0.56 POLB (0.40) —
SCHEMBL9815040 0.56 L3MBTL1 (0.40) INMT
SCHEMBL24052062 0.54 INMT (0.31) INMT
SCHEMBL8740911 0.54 INMT (0.33) INMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION WASHINGTON UNIVERSITY 2023-09-14 — — US disclosed
US-20210393563-A1 METHODS FOR TREATING MICROGLIAL DYSFUNCTION NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-12-23 — — US disclosed
US-9434753-B2 Modified creatine compounds GENCIA CORPORATION (US) 2016-09-06 — — US disclosed
US-20150005258-A1 Modified Creatine Compounds Genci Corporation (US) 2015-01-01 — — US disclosed
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF GENCIA CORPORATION (US) 2014-02-13 — — US disclosed
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof GENCIA CORPORATION (US) 2013-03-21 — — US disclosed
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2012-06-07 — — US disclosed
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-04-14 — — US disclosed
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-01-27 — — US disclosed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 — — US disclosed
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2010-12-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF CS, UQCRC1, UQCRC2 INMT 2619/4885
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20210393563-A1 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CHRNB2, PSEN2, CX3CR1 INMT 2643/4885
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 INMT 3471/4885
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CX3CR1, CD68, FYN INMT 2721/4885
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof UQCRC1, CS, UQCRC2 INMT 2820/4885
US-20150005258-A1 Modified Creatine Compounds CKMT1A; CKMT1B, SLC25A20, ARG2 INMT 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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