SCHEMBL9891455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9891452	0.87	ALDH1A1 (0.48)	ALDH1A1MAPTLMNATOP2AHDAC1
	SCHEMBL15219206	0.84	ALDH1A1 (0.46)	ALDH1A1MAPTLMNATOP2AHDAC1
	SCHEMBL9891458	0.81	ALDH1A1 (0.42)	ALDH1A1MAPTLMNATOP2ACYP3A4
	SCHEMBL9891460	0.81	ALDH1A1 (0.42)	ALDH1A1MAPTLMNATOP2ACYP3A4
	SCHEMBL9756822	0.80	LMNA (0.60)	ALDH1A1MAPTLMNATOP2AHDAC1
	SCHEMBL3880018	0.78	ALDH1A1 (0.52)	ALDH1A1MAPTCYP3A4HDAC1HDAC3
	SCHEMBL30074233	0.78	CES2 (0.47)	ALDH1A1CYP2C19HIF1AALOX15KDM4E
	SCHEMBL5151596	0.77	POLB (0.44)	ALDH1A1MAPTLMNATOP2APOLB
	SCHEMBL9891445	0.77	PDK1 (0.47)	ALDH1A1MAPTHDAC1HDAC3HDAC2
	SCHEMBL18506508	0.77	CYP2C19 (0.47)	ALDH1A1MAPTLMNAHDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.