Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780224 | 0.82 | GAA (0.53) | ALDH1A1GAAKDM4EGLATP53 | |
| SCHEMBL257705 | 0.81 | LMNA (0.44) | ALDH1A1GAAKDM4EGLATP53 | |
| SCHEMBL1679559 | 0.80 | RAPGEF4 (0.52) | ALDH1A1GAAKDM4EGLATP53 | |
| Hydrochloric Acid SCHEMBL28204647 | 0.78 | RAPGEF4 (0.50) | ALDH1A1GAAKDM4EGLATP53 | |
| SCHEMBL3790110 | 0.78 | CYP3A4 (0.54) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL5768693 | 0.78 | RAB9A (0.47) | ALDH1A1GAAKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30780064 | 0.78 | NOX1 (0.55) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL3781932 | 0.78 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4EGLALMNA | |
| SCHEMBL9233011 | 0.78 | NOX1 (0.55) | ALDH1A1GAAKDM4EGLASMN1; SMN2 | |
| SCHEMBL5800763 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EGLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-20260008768-A1 | UREA DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
| WO-2024074651-A1 | SARS-COV-2 MPRO INHIBITORS AND USES THEREOF | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-04-11 | — | — | WO | disclosed |
| CN-117466803-A | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-117209485-A | Pyrimidine skeleton compound with anti-tumor activity and preparation method and application thereof | 四川大学华西医院 | 2023-12-12 | — | — | CN | disclosed |
| EP-4010080-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LTD (GB) | 2023-09-27 | — | — | EP | disclosed |
| CN-111132976-B | Compounds, salts thereof and methods for treating diseases | 阿卡蒂亚药品公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-113874079-A | Bridged tricyclic carbamoylpyridone compounds and pharmaceutical use thereof | 吉利德科学公司 | 2021-12-31 | — | — | CN | disclosed |
| EP-3719015-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2020-10-07 | — | — | EP | disclosed |
| EP-1311160-A4 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INST SCI & TECH (KR) | 2004-04-21 | — | — | EP | disclosed |
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-10-30 | — | — | US | disclosed |
| EP-1311160-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002013611-A1 | 2-PHENYLIMINOTHIAZOLINES, THEIR PREPARATION METHOD AND ANTI-RICE BLAST AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-02-21 | — | — | WO | disclosed |
| WO-1998017631-A2 | SUBSTITUTED OXIME-ETHERS AND THEIR USE AS PESTICIDES | NOVARTIS AG (CH) | 1998-04-30 | — | — | WO | disclosed |
| EP-0013144-B1 | SUBSTITUTED DIPHENYLAMINE DERIVATIVES, COMPOSITIONS AND HERBICIDAL USES THEREOF, AND PROCESSES FOR THEIR PREPARATION | ICI AUSTRALIA LIMITED (AU) | 1983-02-23 | — | — | EP | disclosed |
| US-4315068-A | CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS | RICOH CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0013144-A1 | Substituted diphenylamine derivatives, compositions and herbicidal uses thereof, and processes for their preparation | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |
| US-4101575-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-3981717-A | ANILINO COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008768-A1 | UREA DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | ALDH1A1 1340/4885GAA 1687/4885KDM4E 4547/4885 |
| US-20030203950-A1 | 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same | TYR, SYPL1, SSBP1 | ALDH1A1 4656/4885GAA 2297/4885KDM4E 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.