Sulfuric Acid

Sulfuric Acid

SCHEMBL989869

O=C1C(O)=C(Cl)C(=O)c2ccccc21.O=S(=O)(O)O.[Cu]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 known ✓ Q9NR96 1/20 0.43
MAOA known ✓ P21397 2/20 0.42
MAP2K1 known ✓ Q02750 1/20 0.41
APAF1 O14727 2/20 0.58
TDP2 O95551 2/20 0.58
IDO1 P14902 1/20 0.58
DNMT1 P26358 1/20 0.58
DNMT3L Q9UJW3 1/20 0.58
DNMT3A Q9Y6K1 1/20 0.58
MAPT P10636 5/20 0.46
NPC1 O15118 3/20 0.46
MAPK1 P28482 3/20 0.46
HTT P42858 3/20 0.46
RAB9A P51151 3/20 0.46
NPSR1 Q6W5P4 3/20 0.46
GAA P10253 2/20 0.46
HSP90AA1 P07900 3/20 0.43
HSP90AB1 P08238 2/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2126261 0.92 APAF1 (0.68) APAF1TDP2IDO1DNMT1DNMT3L
SCHEMBL16745426 0.76 APAF1 (0.58) APAF1TDP2IDO1DNMT1DNMT3L
SCHEMBL29678361 0.75 APAF1 (1.00) APAF1TDP2IDO1DNMT1DNMT3L
Dichlon SCHEMBL29360991 0.75 IDO1 (1.00) APAF1TDP2IDO1DNMT1DNMT3L
Dichlon SCHEMBL9751236 0.75 IDO1 (1.00) APAF1TDP2IDO1DNMT1DNMT3L
SCHEMBL461648 0.75 APAF1 (1.00) APAF1TDP2IDO1DNMT1DNMT3L
Anthraquinone SCHEMBL3895044 0.75 MEN1 (0.75) APAF1TDP2IDO1DNMT1DNMT3L
Dichlon SCHEMBL45723 0.75 IDO1 (1.00) APAF1TDP2IDO1DNMT1DNMT3L
SCHEMBL16950365 0.73 IDO1 (0.60) APAF1TDP2IDO1DNMT1DNMT3L
Anthraquinone SCHEMBL28860881 0.73 MEN1 (0.71) APAF1TDP2IDO1DNMT1DNMT3L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2021-11-16 US disclosed
CN-108291055-B Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-07-06 CN disclosed
US-10988611-B2 Crosslinked polyvinylpyrrolidone compositions ISP INVESTMENTS LLC (US) 2021-04-27 US disclosed
CN-112707851-A Sulfur-containing compounds as solvents 诺华丝国际股份有限公司 2021-04-27 CN disclosed
US-10640769-B2 Post-transcriptionally chemically modified double strand RNAs nanoSUR LLC (US) 2020-05-05 US disclosed
US-10426077-B2 Seed flow lubricant compositions and uses thereof 3 Star Ag LLC (US) 2019-10-01 US disclosed
EP-2358768-B1 CROSSLINKED POLYVINYLPYRROLIDONE COMPOSITIONS ISP INVESTMENTS LLC (US) 2019-07-03 EP disclosed
US-20190124916-A1 PROTEIN-BASED FILM COATINGS AND USES THEREOF KAYNE ANDERSON PRIVATE CREDIT, LLC 2019-05-02 US disclosed
EP-3474678-A1 HYDROXY METHIONINE ANALOG FORMULATIONS SUITABLE FOR SPECIALTY CHEMICAL APPLICATIONS Novus International Inc. (US) 2019-05-01 EP disclosed
US-10227551-B2 Sulfur-containing compounds as solvents NOVUS INTERNATIONAL, INC. (US) 2019-03-12 US disclosed
US-5118444-A Mixture of herbicide and amine-oxide surfactant WITCO CORPORATION (US) 1992-06-02 US disclosed
EP-0306222-A2 Benzenesulfonanilide derivatives and fungicides for agriculture and horticulture HOKKO CHEMICAL INDUSTRY CO., LTD (JP) 1989-03-08 EP disclosed
US-H303-H GLYCOSIDE-CONTAINING AGRICULTURAL TREATMENT COMPOSITION A. E. STALEY MANUFACTURING COMPANY (US) 1987-07-07 US disclosed
US-H224-H Glycoside-containing agricultural treatment composition A. E. STALEY MANUFACTURING COMPANY (US) 1987-03-03 US disclosed
US-4512989-A IMIDOESTERS OR IMIDOTHIOESTERS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1985-04-23 US disclosed
US-4420486-A Benzoxazolone derivatives, processes for preparation thereof and compositions containing them HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1983-12-13 US disclosed
US-4391804-A Imidazole derivatives and fungicidal composition containing the same HOKKO CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1983-07-05 US disclosed
US-4304778-A 4-Aminoquinazoline derivatives having fungicidal, anti-insect and acaricidal properties SANKYO COMPANY LIMITED (JP) 1981-12-08 US disclosed
US-4279908-A Pyridazine derivatives and their use as agricultural fungicides SANKYO COMPANY LIMITED (JP) 1981-07-21 US disclosed
US-4052395-A AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES SANKYO COMPANY LIMITED (JA) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227551-B2 Sulfur-containing compounds as solvents TST, CBS, MPST TLR9 4741/4885MAOA 3428/4885MAP2K1 4853/4885
US-11174480-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT TLR9 3762/4885MAOA 3670/4885MAP2K1 895/4885
US-10640769-B2 Post-transcriptionally chemically modified double strand RNAs NSUN2, NSUN3, RNGTT TLR9 3762/4885MAOA 3670/4885MAP2K1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.