SCHEMBL9900889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9900387	0.89	KDR (0.42)	PLA2G7SCN9ABRAFKDR
	SCHEMBL875765	0.87	ALDH1A1 (0.41)	KCNH2HTR2ASLC6A4CDK8PLA2G7
	SCHEMBL876023	0.79	KCNH2 (0.39)	KCNH2HTR2ASLC6A4CDK8PLA2G7
	SCHEMBL9901028	0.77	PLA2G7 (0.38)	KCNH2HTR2ASLC6A4CDK8PLA2G7
	SCHEMBL875574	0.76	KDR (0.44)	CDK8PLA2G7SCN9ABRAFKDR
	SCHEMBL876035	0.76	CDK8 (0.45)	KCNH2HTR2ASLC6A4CDK8PLA2G7
	SCHEMBL13531352	0.73	TRPA1 (0.43)	KCNH2HTR2ASLC6A4CDK8PLA2G7
	SCHEMBL23771636	0.71	AGER (0.53)	KCNH2HTR2ASLC6A4
	SCHEMBL17467929	0.71	ALDH1A1 (0.63)	KCNH2HTR2ASLC6A4CDK8PLA2G7
	SCHEMBL248689	0.71	TRPA1 (0.45)	KCNH2HTR2ASLC6A4CDK8BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.