SCHEMBL990775

SCHEMBL990775

Cc1ccc(S(=O)(=O)CN)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA3 P07451 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA5B Q9Y2D0 1/20 0.56
GAA P10253 2/20 0.54
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
CTSK P43235 1/20 0.50
PSIP1 O75475 1/20 0.48
TLR9 Q9NR96 1/20 0.48
MAPT P10636 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778514 0.82 ALDH1A1 (0.69) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
Hydrochloric Acid SCHEMBL23751236 0.80 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL41372 0.80 ALDH1A1 (0.82) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL63945 0.80 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL86088 0.80 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL10702838 0.78 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL13564611 0.78 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL8788972 0.78 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19CA12
SCHEMBL30474466 0.77 CA2 (0.63) ALDH1A1CA12CA1CA2CA6
SCHEMBL16537421 0.77 ALDH1A1 (0.69) ALDH1A1CYP3A4CYP2C9CYP2C19CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908865-A Synthesis method of p-toluenesulfonyl methyl isonitrile 淮北龙溪生物科技有限公司 2024-11-08 CN claimed
CN-100423951-C Sensitizer dispersion, method for producing same, method for producing mixed dispersion for thermal recording body, and thermal recording body SANKO CO LTD (JP) 2008-10-08 CN claimed
CN-1795108-A Method for producing material containing sensitizer dispersed therein for thermal recording article and thermal recording article SANKO CO LTD (JP) 2006-06-28 CN claimed
WO-2003068204-A1 SYNTHESIS OF SUBSTITUTED SULFONYL AMINES Grünenthal GmbH (DE) 2003-08-21 WO claimed
CN-118772161-A Albumitinib preparation method of intermediate 山东大学 2024-10-15 CN disclosed
US-20240239788-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2024-07-18 US disclosed
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US disclosed
US-20240024346-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2024-01-25 US disclosed
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-02 US disclosed
US-11802111-B2 Cyclobutyl amide monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2023-10-31 US disclosed
WO-2023187833-A1 A NOVEL SALT OF BEMPEDOIC ACID ENALTEC LABS PRIVATE LIMITED (IN) 2023-10-05 WO disclosed
US-11753397-B2 Cereblon binders for the degradation of ikaros C4 THERAPEUTICS, INC. (US) 2023-09-12 US disclosed
CN-1646502-A Triazole derivatives as tachykinin receptor antagonists LILLY CO ELI (US) 2005-07-27 CN disclosed
EP-1554272-A1 BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE ELI LILLY AND COMPANY (US) 2005-07-20 EP disclosed
CN-1185108-C Thermosensitive recording material CIBA SC HOLDING AG (CH) 2005-01-19 CN disclosed
WO-2004014900-A1 BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE ELI LILLY AND COMPANY (US) 2004-02-19 WO disclosed
WO-2003068204-A1 SYNTHESIS OF SUBSTITUTED SULFONYL AMINES Grünenthal GmbH (DE) 2003-08-21 WO disclosed
CN-1330593-A Heat sensitive recording material CIBA SC HOLDING AG (CH) 2002-01-09 CN disclosed
US-4132436-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1979-01-02 US disclosed
US-4119777-A BY OXIDATION OF A THIOAMIDE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1978-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF CYP2C19, CYP3A7, CYP3A5 ALDH1A1 1200/4885CYP3A4 6/4885CYP2C9 5/4885
US-20240024346-A1 CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF ENTPD5, NT5E, ENTPD1 ALDH1A1 425/4885CYP3A4 1184/4885CYP2C9 1046/4885
US-11753397-B2 Cereblon binders for the degradation of ikaros CRBN, IKZF1, IKZF3 ALDH1A1 3363/4885CYP3A4 4129/4885CYP2C9 4731/4885
US-20240239788-A1 SMALL MOLECULE INHIBITORS OF KRAS G12D MUTANT KRAS, NRAS, HRAS ALDH1A1 2871/4885CYP3A4 4645/4885CYP2C9 3953/4885
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS MGLL, LPL, PNLIP ALDH1A1 472/4885CYP3A4 1069/4885CYP2C9 923/4885
US-11802111-B2 Cyclobutyl amide monoacylglycerol lipase modulators MGLL, LPL, PNLIP ALDH1A1 450/4885CYP3A4 1067/4885CYP2C9 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.