Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909175 | 0.85 | MEN1 (0.52) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL40805 | 0.82 | MEN1 (0.50) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL3313335 | 0.82 | MEN1 (0.50) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL94233 | 0.79 | MEN1 (0.54) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL1476944 | 0.79 | SMN1; SMN2 (0.47) | FAAHTSHRLDHASRRALDH1A1 | |
| SCHEMBL1476947 | 0.79 | SMN1; SMN2 (0.47) | FAAHTSHRLDHASRRALDH1A1 | |
| SCHEMBL2417430 | 0.78 | MEN1 (0.46) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL13043948 | 0.77 | LDHA (0.36) | FAAHLDHASRRALDH1A1LMNA | |
| SCHEMBL5909062 | 0.77 | MEN1 (0.62) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL8909886 | 0.76 | MEN1 (0.45) | MEN1KMT2AFAAHMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11008330-B2 | Tetraphenylporphyrin derivative | KYOTO UNIVERSITY (JP) | 2021-05-18 | — | — | US | disclosed |
| US-20200087315-A1 | TETRAPHENYLPORPHYRIN DERIVATIVE | KYOTO UNIVERSITY (JP) | 2020-03-19 | — | — | US | disclosed |
| US-9988392-B2 | 7-beta-alkyl analogs of orvinols | PURDUE PHARMA L.P. (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170204113-A1 | 7-BETA-ALKYL ANALOGS OF ORVINOLS | PURDUE PHARMA L.P. (US) | 2017-07-20 | — | — | US | disclosed |
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160333020-A1 | 7-BETA ANALOGS OF ORVINOLS | PURDUE PHARMA L.P. | 2016-11-17 | — | — | US | disclosed |
| US-20160272640-A1 | SUBSTITUTED PIPERIDIN-4-AMINO-TYPE COMPOUNDS AND USES THEREOF | SHIONOGI & CO., LTD. (JP) | 2016-09-22 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| EP-2948450-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals, Inc. (US) | 2015-12-02 | — | — | EP | disclosed |
| US-9096606-B2 | Quarternized buprenorphine analogs | PURDUE PHARMA, L.P. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150148327-A1 | SUBSTITUTED PYRIDINE SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK CANADA INC. (CA) | 2015-05-28 | — | — | US | disclosed |
| US-20140364448-A1 | QUARTERNIZED BUPRENORPHINE ANALOGS | PURDUE PHARMA L.P. (US) | 2014-12-11 | — | — | US | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |
| US-20140057931-A1 | BUPRENORPHINE ANALOGS | PURDUE PHARMA L.P. (US) | 2014-02-27 | — | — | US | disclosed |
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | MEN1 511/4885KMT2A 1886/4885FAAH 2333/4885 |
| US-20140364448-A1 | QUARTERNIZED BUPRENORPHINE ANALOGS | OPRL1, OPRK1, OPRD1 | MEN1 4841/4885KMT2A 1722/4885FAAH 1139/4885 |
| US-20170204113-A1 | 7-BETA-ALKYL ANALOGS OF ORVINOLS | OPRD1, OPRK1, OPRL1 | MEN1 4265/4885KMT2A 2657/4885FAAH 706/4885 |
| US-20160333020-A1 | 7-BETA ANALOGS OF ORVINOLS | OPRD1, OPRK1, OPRL1 | MEN1 4005/4885KMT2A 2942/4885FAAH 1300/4885 |
| US-20160272640-A1 | SUBSTITUTED PIPERIDIN-4-AMINO-TYPE COMPOUNDS AND USES THEREOF | OPRD1, OPRL1, P2RX4 | MEN1 4671/4885KMT2A 1361/4885FAAH 450/4885 |
| US-11008330-B2 | Tetraphenylporphyrin derivative | PPOX, TTI2, TTI1 | MEN1 1941/4885KMT2A 4347/4885FAAH 4865/4885 |
| US-20200087315-A1 | TETRAPHENYLPORPHYRIN DERIVATIVE | PPOX, TTI2, TTI1 | MEN1 1941/4885KMT2A 4347/4885FAAH 4865/4885 |
| US-20140057931-A1 | BUPRENORPHINE ANALOGS | OPRL1, OPRD1, OPRK1 | MEN1 4742/4885KMT2A 1824/4885FAAH 807/4885 |
| US-20150148327-A1 | SUBSTITUTED PYRIDINE SPLEEN TYROSINE KINASE (SYK) INHIBITORS | SYK, BTK, LYN | MEN1 4348/4885KMT2A 1237/4885FAAH 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.