SCHEMBL9913176

SCHEMBL9913176

CC(CC(C)(C)C)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11922164 1.00 MAPK1 (0.31) MAPK1HRH3
SCHEMBL11922156 1.00 MAPK1 (0.31) MAPK1HRH3
SCHEMBL16104230 0.81
SCHEMBL24791183 0.76
SCHEMBL16316437 0.76
SCHEMBL20995960 0.75 MAPK1 (0.33) MAPK1
SCHEMBL28610109 0.75 HRH3 (0.32) HRH3
SCHEMBL1075261 0.75 MAPK1 (0.40) MAPK1HRH3
SCHEMBL25042721 0.74 MAPK1 (0.31) MAPK1
SCHEMBL21104589 0.73 MAPK1 (0.31) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218523-A1 CORROSION RESISTANT COATING SYSTEMS THE BOEING COMPANY 2024-07-04 US disclosed
US-20240018156-A1 SPIROCYCLIC COMPOUNDS C4 THERAPEUTICS, INC. (US) 2024-01-18 US disclosed
US-20230383148-A1 NONAQUEOUS SOL-GEL FOR ADHESION ENHANCEMENT OF WATER-SENSITIVE MATERIALS THE BOEING COMPANY 2023-11-30 US disclosed
US-20230357595-A1 CORROSION RESISTANT ADHESIVE SOL-GEL THE BOEING COMPANY 2023-11-09 US disclosed
US-20230357592-A1 CORROSION RESISTANT ADHESIVE SOL-GEL THE BOEING COMPANY 2023-11-09 US disclosed
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2023-11-09 US disclosed
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation C4 THERAPEUTICS, INC. (US) 2023-09-07 US disclosed
US-11746245-B2 Soluble corrosion resistant sol-gel THE BOEING COMPANY (US) 2023-09-05 US disclosed
US-11739237-B2 Nonaqueous sol-gel for adhesion enhancement of water-sensitive materials THE BOEING COMPANY (US) 2023-08-29 US disclosed
US-11692113-B2 Nonaqueous sol-gel for adhesion enhancement of water-sensitive materials THE BOEING COMPANY (US) 2023-07-04 US disclosed
US-20180127420-A1 CONDENSED-RING PYRIMIDYLAMINO DERIVATIVE, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) 2018-05-10 US disclosed
US-20170273970-A1 Treatment and/or prophylaxis of TSPO mediated diseases and/or disorders Grünenthal GmbH (DE) 2017-09-28 US disclosed
US-20160297823-A1 SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME INSTITUTE FOR DRUG DISCOVERY, LLC 2016-10-13 US disclosed
WO-2013057267-A1 COMPOSITION COMPRISING A NON-IONIC SURFACTANT AND AN IONIC POLYMER ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2013-04-25 WO disclosed
US-8198473-B2 Process for preparing organically modified siloxanes EVONIK GOLDSCHMIDT GMBH (DE) 2012-06-12 US disclosed
US-20110065196-A1 Trityl Derivatives for Enhancing Mass Spectrometry OXFORD GENE TECHNOLOGY IP LIMITED (GB) 2011-03-17 US disclosed
US-20110065808-A1 CARBONYL COMPOUND REMOVER AJINOMOTO CO. INC. (JP) 2011-03-17 US disclosed
US-20100056818-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES EVONIK GOLDSCHMIDT GMBH (DE) 2010-03-04 US disclosed
US-7635581-B2 Process for preparing organically modified siloxanes GOLDSCHMIDT GMBH (DE) 2009-12-22 US disclosed
US-20070184006-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES GOLDSCHMIDT GMBH (DE) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018156-A1 SPIROCYCLIC COMPOUNDS CRBN, XIAP, RBX1 MAPK1 3405/4885HRH3 4672/4885
US-20170273970-A1 Treatment and/or prophylaxis of TSPO mediated diseases and/or disorders TSPO, TPMT, HLA-DRB1 MAPK1 3508/4885HRH3 457/4885
US-20230357180-A1 DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION STUB1, MDM2, USP30 MAPK1 3828/4885HRH3 4130/4885
US-20110065808-A1 CARBONYL COMPOUND REMOVER C1R, CBR1, CBR3 MAPK1 1312/4885HRH3 36/4885
US-20160297823-A1 SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME CMA1, CHIA, AADAC MAPK1 2351/4885HRH3 30/4885
US-20070184006-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES HSD17B12, CYP51A1, ESD MAPK1 4365/4885HRH3 3419/4885
US-20180127420-A1 CONDENSED-RING PYRIMIDYLAMINO DERIVATIVE, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF PDK1, WEE1, DCK MAPK1 1033/4885HRH3 3039/4885
US-20100056818-A1 PROCESS FOR PREPARING ORGANICALLY MODIFIED SILOXANES HSD17B12, CYP51A1, ESD MAPK1 4365/4885HRH3 3419/4885
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation CRBN, CBL, STUB1 MAPK1 4293/4885HRH3 4378/4885
US-20110065196-A1 Trityl Derivatives for Enhancing Mass Spectrometry PTMS, PTMA, TST MAPK1 4219/4885HRH3 4445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.