SCHEMBL9916232

SCHEMBL9916232

CC(C)c1ccc(-c2cccc3c2sc2ccccc23)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.49
ALOX5 P09917 1/20 0.46
PRKDC P78527 7/20 0.41
GPR3 P46089 1/20 0.39
PIK3CD O00329 2/20 0.37
PIK3CB P42338 2/20 0.37
BRD4 O60885 1/20 0.37
PIK3CA P42336 1/20 0.37
MTOR P42345 1/20 0.37
PIK3CG P48736 1/20 0.37
KCNH2 Q12809 1/20 0.37
BRDT Q58F21 1/20 0.37
MAPT P10636 3/20 0.36
SLC9A1 P19634 1/20 0.35
HTT P42858 1/20 0.35
PAX8 Q06710 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HCRTR1 O43613 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16553319 0.81 ALOX5 (0.61) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL1102404 0.80 GPR3 (0.48) PARP14ALOX5GPR3MAPTSLC9A1
SCHEMBL12996528 0.79 ALOX5 (0.59) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL431845 0.79 ALOX5 (0.59) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL10018846 0.79 ALOX5 (0.59) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL429382 0.79 ALOX5 (0.59) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL9917124 0.79 PARP14 (0.52) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL29350027 0.77 GABRA1 (0.42) L3MBTL1LMNA
SCHEMBL17539967 0.77 PARP14 (0.50) PARP14ALOX5PRKDCGPR3PIK3CD
SCHEMBL14295234 0.77 MAPT (0.46) PARP14ALOX5GPR3MAPTSLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-10355218-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2019-07-16 US disclosed
US-9614160-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-04 US disclosed
US-9614160-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-04 US disclosed
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-03-03 US disclosed
US-9260390-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-16 US disclosed
EP-2468725-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-06-27 EP disclosed
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME MAOA, MAOB, AOC2 PARP14 1883/4885ALOX5 587/4885PRKDC 3657/4885
US-10355218-B2 Aromatic amine derivatives and organic electroluminescent elements using same RER1, NR4A1, REL PARP14 2866/4885ALOX5 1881/4885PRKDC 4590/4885
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 PARP14 2222/4885ALOX5 1407/4885PRKDC 4060/4885
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 PARP14 2222/4885ALOX5 1407/4885PRKDC 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.