Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242381 | 0.82 | FLT1 (0.46) | TDP1LMNAALDH1A1PKMPTGS2 | |
| SCHEMBL305764 | 0.82 | PTGS2 (0.46) | TDP1LMNAALDH1A1HTTMEN1 | |
| SCHEMBL251516 | 0.82 | LMNA (0.50) | TDP1LMNAALDH1A1PKMHTT | |
| SCHEMBL6143116 | 0.82 | LMNA (0.42) | TDP1LMNAALDH1A1PKMHTT | |
| SCHEMBL11792843 | 0.82 | TDP1 (0.42) | TDP1LMNAALDH1A1PKMGAA | |
| SCHEMBL17985 | 0.80 | LMNA (0.47) | TDP1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL733946 | 0.80 | TSHR (0.51) | LMNAALDH1A1PKMHTTGAA | |
| SCHEMBL18593 | 0.80 | BRD1 (0.42) | TDP1LMNAALDH1A1HSD17B10PTGS2 | |
| SCHEMBL6143117 | 0.80 | ESR1 (0.47) | TDP1LMNAALDH1A1PKMGAA | |
| SCHEMBL7546641 | 0.80 | LMNA (0.41) | TDP1LMNAALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490439-A | Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent | 苏州华道生物药业股份有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-1322708-A | Preparation of di-tert-butyl dicarbonate | YU BAIXING (CN) | 2001-11-21 | — | — | CN | claimed |
| CN-117659017-B | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2026-05-15 | — | — | CN | disclosed |
| US-12479821-B2 | Quinoline compound and use thereof | MBD Co., Ltd. (KR) | 2025-11-25 | — | — | US | disclosed |
| US-12391647-B2 | Benzamide compound and preparation method, use, and pharmaceutical composition thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2025-08-19 | — | — | US | disclosed |
| CN-119490439-A | Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent | 苏州华道生物药业股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| US-20240277683-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2024-08-22 | — | — | US | disclosed |
| US-20240254083-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. | 2024-08-01 | — | — | US | disclosed |
| EP-4337206-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | Libra Therapeutics, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-117659017-A | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2024-03-08 | — | — | CN | disclosed |
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. | 2024-02-29 | — | — | US | disclosed |
| EP-0627443-A1 | 3,4'-DIDEOXYMYCAMINOSYLTYLONOLIDE DERIVATIVE AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5248828-A | Method for preparing sulfones | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-09-28 | — | — | US | disclosed |
| US-5235084-A | METHOD FOR PREPARING SULFONES | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0508424-A2 | Method for preparing sulfones | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-4960903-A | Aromatic compounds having sulfonyl groups | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0233409-B1 | AROMATIC SULFONYL COMPOUNDS | Tonen Corporation (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0233409-A2 | Aromatic sulfonyl compounds | Tonen Corporation (JP) | 1987-08-26 | — | — | EP | disclosed |
| US-4507315-A | Hypoglycaemic and hypolipidaemic benzamide substituted (1H-) imidazole derivatives and compositions | MAY & BAKER LIMITED (GB) | 1985-03-26 | — | — | US | disclosed |
| US-4164395-A | USING A SULFONYL OXIME AS ACTIVATOR | FMC CORPORATION (US) | 1979-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479821-B2 | Quinoline compound and use thereof | CYP4A11, CYP7A1, CYP4B1 | TDP1 3486/4885LMNA 3175/4885ALDH1A1 647/4885 |
| US-12391647-B2 | Benzamide compound and preparation method, use, and pharmaceutical composition thereof | JAK2, STAT3, STAT5A | TDP1 4486/4885LMNA 2434/4885ALDH1A1 635/4885 |
| US-20240277683-A1 | COMPOUNDS | SLC10A1, ABCB11, REN | TDP1 4542/4885LMNA 2065/4885ALDH1A1 951/4885 |
| US-20240254083-A1 | HETEROCYCLIC TRPML1 AGONISTS AND USES THEREOF | TRPM2, TRPM7, TRPM8 | TDP1 2769/4885LMNA 2150/4885ALDH1A1 2748/4885 |
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | MPO, CAT, SOD1 | TDP1 134/4885LMNA 2736/4885ALDH1A1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.