Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.60 |
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | KIF11 | P52732 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 4/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | GCKR | Q14397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690424 | 0.84 | KIF11 (0.61) | MAOBKDM1AKIF11CASP1 | |
| SCHEMBL28530523 | 0.84 | KIF11 (0.61) | MAOBKDM1AKIF11CASP1 | |
| SCHEMBL30337692 | 0.84 | METAP2 (0.45) | MAOBKDM1A | |
| SCHEMBL8974216 | 0.84 | METAP2 (0.45) | MAOBKDM1A | |
| SCHEMBL14988472 | 0.84 | KDM1A (0.61) | MAOBKDM1AKIF11PTGS1FEN1 | |
| SCHEMBL4342508 | 0.82 | KIF11 (0.59) | MAOBKDM1AKIF11CASP1 | |
| SCHEMBL18078706 | 0.82 | KDM1A (0.57) | MAOBKDM1AKIF11FEN1ALOX5AP | |
| SCHEMBL27344645 | 0.82 | KIF11 (0.63) | MAOBKDM1AKIF11FEN1ALOX5AP | |
| SCHEMBL30087143 | 0.82 | METAP2 (0.48) | MAOBKDM1A | |
| SCHEMBL6804411 | 0.82 | METAP2 (0.48) | MAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042658-B1 | MEDICINAL COMPOSITION IMPROVING LEPTIN RESISTANCE | UNIV KYOTO (JP) | 2019-01-16 | — | — | EP | disclosed |
| WO-2018051252-A2 | NOVEL AMIDE COMPOUND, METHOD FOR PRODUCING THE SAME, AND MITICIDE | INSECTICIDES (INDIA) LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |
| US-9573887-B2 | Naphthalene derivative | DAITO CHEMIX CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| EP-2599771-B1 | NAPHTHALENE DERIVATIVE | DAITO CHEMIX CORP (JP) | 2016-09-14 | — | — | EP | disclosed |
| US-9206129-B2 | Agent for treatment of eye diseases | DAITO CHEMIX CORPORATION (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20150266861-A1 | Glucagon Receptor Modulators | PFIZER INC. (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150266861-A1 | Glucagon Receptor Modulators | PFIZER INC. (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150266861-A1 | Glucagon Receptor Modulators | PFIZER INC. (US) | 2015-09-24 | — | — | US | disclosed |
| EP-2623494-B1 | AGENT FOR TREATMENT OF EYE DISEASES | DAITO CHEMIX CORP (JP) | 2015-09-02 | — | — | EP | disclosed |
| CN-103261165-B | Glucagon receptor modulators | PFIZER INC. (US) | 2015-08-26 | — | — | CN | disclosed |
| US-7795471-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7795471-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20090221817-A1 | Triethylamine was added dropwise to a solution of 2-methylpropane-2-sulfinyl chloride and methyl trans-4-amino-1-cyclohexane carboxylate p-toluenesulfonate in tetrahydrofuran solvent to obtain Methyl trans-4-(2-methylpropane-2-sulfonylamino)cyclohexanecarboxylate; hydrolysis; oxidation; intermediates | SHIONOGI & CO., LTD. (JP) | 2009-09-03 | — | — | US | disclosed |
| US-20090221817-A1 | Triethylamine was added dropwise to a solution of 2-methylpropane-2-sulfinyl chloride and methyl trans-4-amino-1-cyclohexane carboxylate p-toluenesulfonate in tetrahydrofuran solvent to obtain Methyl trans-4-(2-methylpropane-2-sulfonylamino)cyclohexanecarboxylate; hydrolysis; oxidation; intermediates | SHIONOGI & CO., LTD. (JP) | 2009-09-03 | — | — | US | disclosed |
| US-7547800-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-7547800-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20090043094-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20090043094-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-7314950-B2 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314950-B2 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043094-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | ACMSD, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AADAT | MAOB 1709/4885KDM1A 1332/4885KIF11 3353/4885 |
| US-20090221817-A1 | Triethylamine was added dropwise to a solution of 2-methylpropane-2-sulfinyl chloride and methyl trans-4-amino-1-cyclohexane carboxylate p-toluenesulfonate in tetrahydrofuran solvent to obtain Methyl trans-4-(2-methylpropane-2-sulfonylamino)cyclohexanecarboxylate; hydrolysis; oxidation; intermediates | TST, ACMSD, PNMT | MAOB 1506/4885KDM1A 359/4885KIF11 4584/4885 |
| US-20150266861-A1 | Glucagon Receptor Modulators | GLP1R, GCGR, GPR119 | MAOB 2356/4885KDM1A 3632/4885KIF11 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.