Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 6/20 | 0.47 |
| ▸ | IDO1 | P14902 | 5/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953501 | 0.88 | HPD (0.47) | GLATDO2IDO1IDO2L3MBTL1 | |
| SCHEMBL9952718 | 0.88 | TDO2 (0.48) | GLATDO2IDO1IDO2L3MBTL1 | |
| SCHEMBL9954119 | 0.87 | HCAR1 (0.52) | GLATDO2IDO2L3MBTL1 | |
| SCHEMBL9952904 | 0.85 | GLA (0.51) | GLATDO2IDO1IDO2L3MBTL1 | |
| SCHEMBL9953129 | 0.81 | POLB (0.41) | TDO2IDO1IDO2POLB | |
| SCHEMBL9954657 | 0.80 | HPD (0.44) | TDO2IDO1IDO2POLB | |
| SCHEMBL30632412 | 0.80 | TDO2 (0.52) | TDO2IDO1IDO2 | |
| SCHEMBL9954749 | 0.80 | PDE7A (0.45) | — | |
| SCHEMBL9955332 | 0.78 | HCAR1 (0.51) | TDO2IDO1IDO2TP53POLB | |
| SCHEMBL9954234 | 0.78 | ALDH1A1 (0.53) | TDO2IDO2TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |