Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24320108 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL30516932 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL9953980 | 0.82 | ATM (0.51) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL9954930 | 0.81 | POLB (0.58) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL2926644 | 0.81 | KMT2A (0.41) | MEN1KMT2AHTTUSP2MAPT | |
| SCHEMBL9953464 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL9954470 | 0.77 | HCAR1 (0.46) | ALDH1A1MEN1KMT2AATMHTT | |
| SCHEMBL9954589 | 0.76 | ALOX12 (0.50) | ALDH1A1MEN1KMT2AATMMAPT | |
| SCHEMBL24320125 | 0.75 | MEN1 (0.52) | ALDH1A1KDM4EMEN1KMT2AATM | |
| SCHEMBL9954662 | 0.74 | PI4KA (0.47) | KDM4EMEN1KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |