Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 10/20 | 0.48 |
| ▸ | IDO1 | P14902 | 9/20 | 0.48 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 0.48 |
| ▸ | HPD | P32754 | 2/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954358 | 0.88 | ALDH1A1 (0.53) | TDO2IDO2HPDPOLBPDE4D | |
| SCHEMBL9952904 | 0.88 | GLA (0.51) | TDO2IDO1IDO2PI4KAPIK3CG | |
| SCHEMBL9952718 | 0.86 | TDO2 (0.48) | TDO2IDO1IDO2HPDGLA | |
| SCHEMBL9954001 | 0.84 | PDE4D (0.56) | HPDPI4KAPIK3CGPDE4DL3MBTL1 | |
| SCHEMBL9953739 | 0.83 | HPD (0.47) | TDO2IDO1IDO2HPDPI4KA | |
| SCHEMBL9954651 | 0.81 | POLB (0.53) | TDO2IDO1IDO2HPDPI4KA | |
| SCHEMBL9954671 | 0.80 | HCAR1 (0.52) | TDO2IDO2HPDGLAPDE4D | |
| SCHEMBL9954423 | 0.79 | POLB (0.41) | TDO2IDO1IDO2PI4KAPIK3CG | |
| SCHEMBL9953665 | 0.78 | TGM2 (0.45) | HPDPI4KAPIK3CG | |
| SCHEMBL9953497 | 0.78 | PDE4D (0.43) | PI4KAPIK3CGPDE4DL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |