SCHEMBL9958445

SCHEMBL9958445

COC(=O)[C@@H](N)Cc1ccc(F)c(O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
SLC7A5 Q01650 3/20 0.49
LCK P06239 2/20 0.49
PTGS2 P35354 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
EGFR P00533 1/20 0.49
FYN P06241 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
ALOX15 P16050 1/20 0.49
PTGS1 P23219 1/20 0.49
HTR2A P28223 1/20 0.49
RECQL P46063 1/20 0.49
HIF1A Q16665 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MEP1B Q16820 1/20 0.43
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11252319 0.88 ALDH1A1 (0.51) ALDH1A1SLC7A5LCKPTGS2KDM4E
SCHEMBL11252329 0.88 ALDH1A1 (0.51) ALDH1A1SLC7A5LCKPTGS2KDM4E
SCHEMBL6706478 0.88 ALDH1A1 (0.53) ALDH1A1SLC7A5LCKPTGS2KDM4E
SCHEMBL16059778 0.88 ALDH1A1 (0.53) ALDH1A1SLC7A5LCKPTGS2KDM4E
SCHEMBL16060230 0.88 ALDH1A1 (0.53) ALDH1A1SLC7A5LCKPTGS2KDM4E
Hydrochloric Acid SCHEMBL30832116 0.87 ALDH1A1 (0.53) ALDH1A1SLC7A5LCKPTGS2KDM4E
Hydrochloric Acid SCHEMBL21623775 0.87 ALDH1A1 (0.53) ALDH1A1SLC7A5LCKPTGS2KDM4E
Hydrochloric Acid SCHEMBL6706475 0.87 ALDH1A1 (0.55) ALDH1A1SLC7A5LCKPTGS2KDM4E
Hydrochloric Acid SCHEMBL29728759 0.87 ALDH1A1 (0.55) ALDH1A1SLC7A5LCKPTGS2KDM4E
Hydrochloric Acid SCHEMBL4037085 0.87 ALDH1A1 (0.55) ALDH1A1SLC7A5LCKPTGS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568976-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY Aviko Radiopharmaceuticals, LLC (US) 2025-06-18 EP disclosed
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS LLC (US) 2024-02-29 US disclosed
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS LLC (US) 2024-02-29 US disclosed
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS LLC (US) 2024-02-29 US disclosed
WO-2024035871-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS, LLC (US) 2024-02-15 WO disclosed
EP-3427737-A1 SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION NeuroVive Pharmaceutical AB (SE) 2019-01-16 EP disclosed
EP-2654753-B1 SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION NEUROVIVE PHARMACEUTICAL AB (SE) 2018-10-31 EP disclosed
EP-2770977-B1 NOVEL DOSAGE FORM NEUROVIVE PHARMACEUTICAL AB (SE) 2017-07-12 EP disclosed
US-9504728-B2 Dosage form NEUROVIVE PHARMACEUTICAL AB (SE) 2016-11-29 US disclosed
US-9271977-B2 Sanglifehrin derivatives and methods for their production NEUROVIVE PHARMACEUTICAL AB (SE) 2016-03-01 US disclosed
EP-2691413-B1 MACROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION NEUROVIVE PHARMACEUTICAL AB (SE) 2014-12-24 EP disclosed
EP-2770977-A1 NOVEL DOSAGE FORM Neurovive Pharmaceutical AB (SE) 2014-09-03 EP disclosed
US-20140234414-A1 Novel Dosage Form Abliva Ab (SE) 2014-08-21 US disclosed
US-20140080837-A1 Sanglifehrin Derivatives and Methods for Their Production Neurovive Pharmaceuticals AB (SE) 2014-03-20 US disclosed
US-20140038885-A1 Macrocyclic Compounds and Methods for Their Production NEUROVIVE PHARMACEUTICAL AB (SE) 2014-02-06 US disclosed
EP-2691413-A1 MACROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION Neurovive Pharmaceutical AB (SE) 2014-02-05 EP disclosed
EP-2654753-A1 SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION Neurovive Pharmaceutical AB (SE) 2013-10-30 EP disclosed
WO-2013061052-A1 NOVEL DOSAGE FORM BIOTICA TECHNOLOGY LIMITED (GB) 2013-05-02 WO disclosed
WO-2012131377-A1 MACROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2012-10-04 WO disclosed
WO-2012085553-A1 SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2012-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234414-A1 Novel Dosage Form SI, RAB10, SAMM50 ALDH1A1 2618/4885SLC7A5 1786/4885LCK 4416/4885
US-20140080837-A1 Sanglifehrin Derivatives and Methods for Their Production MAVS, HDGF, TTPA ALDH1A1 2545/4885SLC7A5 4617/4885LCK 2754/4885
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY NME2, BTD, BLVRB ALDH1A1 4513/4885SLC7A5 56/4885LCK 3709/4885
US-20140038885-A1 Macrocyclic Compounds and Methods for Their Production HAVCR2, RPL35, CD4 ALDH1A1 2007/4885SLC7A5 1425/4885LCK 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.