Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.68 |
| ▸ | CA1 | P00915 | 17/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL4450032 | 0.97 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1006722 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL166041 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL8997649 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL2841686 | 0.93 | CA2 (0.78) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL6665082 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL10900872 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1535442 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL20704875 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL21958268 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12139608-B2 | Non-halogenated flame retardant polyamide compositions | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2024-11-12 | — | — | US | claimed |
| EP-4291595-A1 | METAL ORGANIC FRAMEWORKS COMPRISING COPPER IONS AND PROCESSES FOR PREPARING SAME | RJ Lee Group, Inc. (US) | 2023-12-20 | — | — | EP | claimed |
| US-20220272982-A1 | METAL ORGANIC FRAMEWORKS COMPRISING COPPER IONS AND PROCESSES FOR PREPARING SAME | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2022-09-01 | — | — | US | claimed |
| WO-2022174270-A1 | METAL ORGANIC FRAMEWORKS COMPRISING COPPER IONS AND PROCESSES FOR PREPARING SAME | RJ LEE GROUP, INC. (US) | 2022-08-18 | — | — | WO | claimed |
| CN-114685844-A | Preparation method of efficient oil-water separation sponge | 中国石油大学(华东) | 2022-07-01 | — | — | CN | claimed |
| EP-3947563-A1 | NON-HALOGENATED FLAME RETARDANT POLYAMIDE COMPOSITIONS | Ascend Performance Materials Operations LLC (US) | 2022-02-09 | — | — | EP | claimed |
| CN-113661214-A | Non-halogenated flame retardant polyamide composition | 奥升德功能材料运营有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-112011705-A | Batch preparation method of nano-carbon reinforced copper-based composite material | 哈尔滨工业大学 | 2020-12-01 | — | — | CN | claimed |
| CN-112011706-A | Batch preparation method of carbon nanosheet reinforced copper-based composite material | 哈尔滨工业大学 | 2020-12-01 | — | — | CN | claimed |
| WO-2020205988-A1 | NON-HALOGENATED FLAME RETARDANT POLYAMIDE COMPOSITIONS | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2020-10-08 | — | — | WO | claimed |
| US-20110118490-A1 | Porous Organic-Inorganic Hybrid Materials with Crystallinity and Method for Preparing Thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KP) | 2011-05-19 | — | — | US | claimed |
| US-20110067426-A1 | Apparatus for Treating Air | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KP) | 2011-03-24 | — | — | US | claimed |
| CN-101475790-A | Novel timber adhesive and preparation thereof | GUANG YANG (CN) | 2009-07-08 | — | — | CN | claimed |
| US-20060052646-A1 | Process for producing ether compounds in presence of a copper (II) salt | SHOWA DENKO K.K. (JP) | 2006-03-09 | — | — | US | claimed |
| EP-1551552-A1 | PROCESS FOR PRODUCING ETHER COMPOUNDS IN PRESENCE OF A COPPER (II) SALT | Showa Denko K.K. (JP) | 2005-07-13 | — | — | EP | claimed |
| EP-0727608-B1 | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO LTD (JP) | 2004-09-01 | — | — | EP | claimed |
| WO-2003106024-A1 | PROCESS FOR PRODUCING ETHER COMPOUNDS IN PRESENCE OF A COPPER (II) SALT | SHOWA DENKO K. K. (JP) | 2003-12-24 | — | — | WO | claimed |
| US-5862796-A | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO., LTD. (JP) | 1999-01-26 | — | — | US | claimed |
| EP-0727608-A2 | Gas storage apparatus, gaseous fuel automobile using the gas storage apparatus, gas storage method and methane adsorbing-retaining agent | OSAKA GAS CO., LTD. (JP) | 1996-08-21 | — | — | EP | claimed |
| US-3961933-A | ALGICIDAL COMPOSITION FOR NON-MEDICAL USESMICROBIOCIDES, COPPER TEREPHTHALATE AND ISOPHTHALATE, INORGANIC COPPER SALT | TOKYO ORGANIC CHEMICAL INDUSTRIES, INC. (JA) | 1976-06-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052646-A1 | Process for producing ether compounds in presence of a copper (II) salt | ADH1C, AKR7A2, ADH1A | CA2 535/4885CA1 588/4885CA4 400/4885 |
| US-20220272982-A1 | METAL ORGANIC FRAMEWORKS COMPRISING COPPER IONS AND PROCESSES FOR PREPARING SAME | PUF60, YIF1A, SOD1 | CA2 2710/4885CA1 3106/4885CA4 2956/4885 |
| US-20110118490-A1 | Porous Organic-Inorganic Hybrid Materials with Crystallinity and Method for Preparing Thereof | ATM, TPR, BMP2 | CA2 212/4885CA1 242/4885CA4 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.