SCHEMBL9968783

SCHEMBL9968783

CCOc1ccc(Nc2ccc(C(c3ccc(N(CC)Cc4cccc(C)c4)cc3)c3ccc(N(CC)Cc4cccc(S(=O)(=O)O)c4)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 3/20 0.47
P2RX7 Q99572 2/20 0.47
CNR2 P34972 3/20 0.40
CNR1 P21554 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
APEX1 P27695 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
MAPT P10636 4/20 0.39
MAPK1 P28482 2/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12256273 0.93 SNCA (0.49) SNCAP2RX7CNR2CNR1TDP1
SCHEMBL15868117 0.90 SNCA (0.51) SNCAP2RX7TDP1MEN1THRB
SCHEMBL9968787 0.89 SNCA (0.51) SNCAP2RX7CNR2TDP1MEN1
SCHEMBL9908981 0.87 MAPT (0.44) SNCAP2RX7CNR2MAPTMAPK1
SCHEMBL1107139 0.87 SNCA (0.49) SNCAP2RX7CNR2TDP1MEN1
SCHEMBL26772615 0.86 CNR2 (0.52) CNR2CNR1TDP1MEN1THRB
SCHEMBL9968784 0.86 CNR2 (0.52) CNR2CNR1TDP1MEN1THRB
SCHEMBL19428161 0.86 THRB (0.43) SNCAP2RX7CNR2CNR1TDP1
SCHEMBL9968788 0.83 CNR2 (0.47) CNR2CNR1TDP1MEN1THRB
SCHEMBL14499815 0.81 THRB (0.53) CNR2CNR1TDP1MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365953-A1 Variants and Compositions Comprising Variants with High Stability in Presence of a Chelating Agent NOVOZYMES A/S (DK) 2023-11-16 US disclosed
US-20160348043-A1 HIGH-EFFICIENCY PERFUME CAPSULES PROCTER & GAMBLE (US) 2016-12-01 US disclosed
US-9493730-B2 Cleaning composition comprising amylase variants with high stability in the presence of a chelating agent THE PROCTER & GAMBLE COMPANY (US) 2016-11-15 US disclosed
US-20140249069-A1 HIGH-EFFICIENCY PERFUME CAPSULES THE PROCTER & GAMBLE COMPANY (US) 2014-09-04 US disclosed
US-8785171-B2 Fabric and home care products comprising cold water proteases THE PROCTER & GAMBLE COMPANY (US) 2014-07-22 US disclosed
US-20140193888-A1 FABRIC AND HOME CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2014-07-10 US disclosed
US-8759275-B2 High-efficiency perfume capsules THE PROCTOR & GAMBLE COMPANY (US) 2014-06-24 US disclosed
US-8586521-B2 Method of laundering fabrics at low temperature THE PROCTER & GAMBLE COMPANY (US) 2013-11-19 US disclosed
US-8449626-B2 Cleaning method THE PROCTER & GAMBLE COMPANY (US) 2013-05-28 US disclosed
US-20120151684-A1 METHOD OF LAUNDERING FABRICS AT LOW TEMPERATURE PROCTER & GAMBLE COMPANY, THE 2012-06-21 US disclosed
US-20110257065-A1 Detergent Composition THE PROCTER & GAMBLE COMPANY 2011-10-20 US disclosed
US-20110237487-A1 FABRIC AND HOME CARE PRODUCTS THE PROCTER & GAMBLE COMPANY 2011-09-29 US disclosed
US-20110212876-A1 CLEANING COMPOSITION COMPRISING AMYLASE VARIANTS WITH HIGH STABILITY IN THE PRESENCE OF A CHELATING AGENT THE PROCTER & GAMBLE COMPANY 2011-09-01 US disclosed
US-20110195481-A1 Variants And Compositions Comprising Variants With High Stability In Presence Of A Chelating Agent NOVOZYMES A/S (DK) 2011-08-11 US disclosed
US-20110111999-A1 HIGH-EFFICIENCY PERFUME CAPSULES THE PROCTER & GAMBLE COMPANY 2011-05-12 US disclosed
US-20110107527-A1 CLEANING METHOD THE PROCTER & GAMBLE COMPANY 2011-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110107527-A1 CLEANING METHOD CAT, MPO, LBR SNCA 391/4885P2RX7 2403/4885CNR2 4683/4885
US-20110111999-A1 HIGH-EFFICIENCY PERFUME CAPSULES PLIN5, PORCN, PIGS SNCA 2707/4885P2RX7 2867/4885CNR2 549/4885
US-20160348043-A1 HIGH-EFFICIENCY PERFUME CAPSULES PLIN5, PORCN, PIGS SNCA 2707/4885P2RX7 2867/4885CNR2 549/4885
US-20110195481-A1 Variants And Compositions Comprising Variants With High Stability In Presence Of A Chelating Agent RNASE1, AMY2A, AMY1A SNCA 918/4885P2RX7 3835/4885CNR2 4708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.