Sugi Predict

Sugi Predict / Compounds / SCHEMBL9980433

SCHEMBL9980433

SCHEMBL9980433

Ic1cnc2cccnc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.43
▸ KDM4E B2RXH2 3/20 0.39
▸ MAPT P10636 2/20 0.39
▸ NPC1 O15118 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ CASP1 P29466 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ CASP7 P55210 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ NR4A2 P43354 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ HSP90AB1 P08238 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274826 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL30099834 0.75 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL8194 0.75 ALDH1A1 (0.67) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL12066725 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL19445102 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL1771992 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL2009983 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL130023 0.74 CYP1A2 (0.55) ALDH1A1KDM4EMAPTCYP1A2ATAD2
SCHEMBL4141544 0.74 BCHE (0.44) ALDH1A1KDM4EMAPTNPC1POLB
SCHEMBL335171 0.74 HTT (0.53) ALDH1A1KDM4EMAPTNPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230180606-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 — — US disclosed
US-11569454-B2 Organic light-emitting device and display apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-31 — — US disclosed
WO-2022161420-A1 CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翊石医药科技有限公司 2022-08-04 — — WO disclosed
US-11355711-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-07 — — US disclosed
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 — — US disclosed
US-11251376-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-15 — — US disclosed
US-11165024-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-02 — — US disclosed
US-20210184119-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-06-17 — — US disclosed
US-10865216-B2 Tricyclic Gyrase inhibitors MERCK SHARP & DOHME CORP. (US) 2020-12-15 — — US disclosed
US-10858360-B2 Tricyclic gyrase inhibitors MERCK SHARP & DOHME CORP. (US) 2020-12-08 — — US disclosed
WO-2013071264-A1 COMBINATION OF KINASE INHIBITORS AND USES THEREOF INTELLIKINE, LLC (US) 2013-05-16 — — WO disclosed
EP-2575462-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Intellikine, LLC (US) 2013-04-10 — — EP disclosed
US-20120294930-A1 COMBINATION OF KINASE INHIBITORS AND USES THEREOF INTELLIKINE LLC (US) 2012-11-22 — — US disclosed
US-20120294930-A1 COMBINATION OF KINASE INHIBITORS AND USES THEREOF INTELLIKINE LLC (US) 2012-11-22 — — US disclosed
WO-2012148540-A1 COMBINATION OF KANASE INHIBITORS AND USES THREOF INTELLIKINE, LLC (US) 2012-11-01 — — WO disclosed
WO-2012125746-A1 TRICYCLIC GYRASE INHIBITORS TRIUS THERAPEUTICS INC. (US) 2012-09-20 — — WO disclosed
US-20120238751-A1 TRICYCLIC GYRASE INHIBITORS TRIUS THERAPEUTICS, INC. (US) 2012-09-20 — — US disclosed
US-20120238751-A1 TRICYCLIC GYRASE INHIBITORS TRIUS THERAPEUTICS, INC. (US) 2012-09-20 — — US disclosed
WO-2011149937-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INTELLIKINE, INC. (US) 2011-12-01 — — WO disclosed
WO-2011149937-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INTELLIKINE, INC. (US) 2011-12-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 ALDH1A1 450/4885KDM4E 2540/4885MAPT 735/4885
US-20120238751-A1 TRICYCLIC GYRASE INHIBITORS TOP1, TOP2A, TOP2B ALDH1A1 1898/4885KDM4E 2371/4885MAPT 2765/4885
US-11251376-B2 Heterocyclic compound and organic light-emitting device including the same LAGE3, DDT, AOC2 ALDH1A1 57/4885KDM4E 2096/4885MAPT 1882/4885
US-11355711-B2 Organic light-emitting device EML4, FTO, L1CAM ALDH1A1 245/4885KDM4E 2653/4885MAPT 797/4885
US-10858360-B2 Tricyclic gyrase inhibitors TOP1, TOP2A, TOP2B ALDH1A1 1898/4885KDM4E 2371/4885MAPT 2765/4885
US-10865216-B2 Tricyclic Gyrase inhibitors TOP1, TOP2A, TOP2B ALDH1A1 1726/4885KDM4E 2335/4885MAPT 2972/4885
US-20120294930-A1 COMBINATION OF KINASE INHIBITORS AND USES THEREOF MTOR, AKT2, MTMR1 ALDH1A1 4563/4885KDM4E 2754/4885MAPT 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.