Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718221 | 0.80 | KDM4E (0.37) | KMT2AL3MBTL1ALDH1A1TSHRHTT | |
| SCHEMBL7781747 | 0.77 | HTR3A (0.43) | NOTUMCYP1A2CYP2A6ALDH1A1POLB | |
| SCHEMBL29136204 | 0.73 | HTT (0.45) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL13045101 | 0.69 | BIRC5 (0.51) | FAAHMGLLMETAP2KEAP1SLC6A2 | |
| SCHEMBL30918020 | 0.67 | CYP11B2 (0.54) | ADORA3ADORA2AADORA1POLB | |
| SCHEMBL20239638 | 0.66 | L3MBTL1 (0.59) | FAAHMGLLMETAP2ADORA3ADORA2A | |
| SCHEMBL2073630 | 0.64 | CDK4 (0.32) | KMT2ACYP2A6SLC6A2ALDH1A1MAPT | |
| SCHEMBL650735 | 0.64 | NOS2 (0.34) | L3MBTL1NOTUMCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL16720346 | 0.64 | HPGDS (0.39) | FAAHMGLLMETAP2KEAP1KMT2A | |
| SCHEMBL29136188 | 0.63 | RAB9A (0.42) | MEN1KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163195-A1 | FUSED PYRROLE DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-12-29 | — | — | WO | disclosed |