SCHEMBL9999649

SCHEMBL9999649

C=CCc1ccc(O)c(CO)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.66
GABRA1 P14867 8/20 0.63
GABRB2 P47870 8/20 0.63
CNR2 P34972 3/20 0.63
MAPT P10636 3/20 0.63
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 2/20 0.63
GAA P10253 2/20 0.63
CNR1 P21554 2/20 0.63
KMT2A Q03164 2/20 0.63
PPARG P37231 2/20 0.63
PPARD Q03181 2/20 0.63
KDM4E B2RXH2 1/20 0.63
ALDH2 P05091 1/20 0.63
AKR1B1 P15121 1/20 0.63
HPGD P15428 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
ALOX5 P09917 4/20 0.58
POLB P06746 2/20 0.58
GABRB1 P18505 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821126 0.88 GABRA1 (0.72) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL7656092 0.86 XDH (0.68) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL7412533 0.85 GABRA1 (0.63) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL28956633 0.83 XDH (0.63) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL19248511 0.83 XDH (0.48) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL7567997 0.83 XDH (0.63) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL7110975 0.82 XDH (0.52) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL29188764 0.82 TNKS (0.72) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL30876046 0.82 TNKS (0.72) XDHGABRA1GABRB2CNR2MAPT
SCHEMBL10824189 0.80 XDH (0.59) XDHGABRA1GABRB2CNR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269440-B Damper for sports equipment and sports equipment comprising damper VT超科有限责任公司 2023-12-12 CN disclosed
WO-2023154714-A1 VIBRATION DAMPENING TAPE FOR ATTACHING A GRIPPING MEMBER AND METHOD OF USE VT Advantec, L.L.C. (US) 2023-08-17 WO disclosed
EP-4003549-A1 DAMPENERS FOR SPORTING EQUIPMENT AND SPORTING EQUIPMENT INCLUDING THE SAME VT Advantec, LLC (US) 2022-06-01 EP disclosed
CN-114269440-A Damper for sports equipment and sports equipment comprising damper VT超科有限责任公司 2022-04-01 CN disclosed
US-20180093939-A9 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2018-04-05 US disclosed
US-9889222-B2 Aqueous medium-sensitive coating compositions for triggered release of active ingredients and visual indication for wetness KIMBERLY-CLARK WORLDWIDE, INC. (US) 2018-02-13 US disclosed
US-20170240710-A1 POLYSILOXANE-POLYCARBONATE COPOLYMERS AND METHOD FOR PRODUCTION THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-24 US disclosed
US-20170233325-A1 NOVEL MONOMERS FROM BIOMASS NDSU RESEARCH FOUNDATION (US) 2017-08-17 US disclosed
US-9661856-B1 Synergy of plant antimicrobials with silver THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-05-30 US disclosed
US-9585826-B2 Triggerable compositions for two-stage, controlled release of active chemistry KIMBERLY-CLARK WORLDWIDE, INC. (US) 2017-03-07 US disclosed
US-20140128827-A1 TRIGGERABLE COMPOSITIONS FOR TWO-STAGE, CONTROLLED RELEASE OF ACTIVE CHEMISTRY KIMBERLY-CLARK WORLDWIDE, INC. (US) 2014-05-08 US disclosed
US-20130267501-A1 Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2013-10-10 US disclosed
US-20130203715-A1 USE OF TRP CHANNEL AGONISTS TO TREAT INFECTIONS PULMATRIX, INC. (US) 2013-08-08 US disclosed
US-20120291793-A1 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES R.J. REYNOLDS TOBACCO COMPANY 2012-11-22 US disclosed
US-20120028907-A1 METHODS FOR IDENTIFICATION OF TUMOR PHENOTYPE AND TREATMENT INTELLIGENT ONCOTHERAPEUTICS, INC. (US) 2012-02-02 US disclosed
US-20120028907-A1 METHODS FOR IDENTIFICATION OF TUMOR PHENOTYPE AND TREATMENT INTELLIGENT ONCOTHERAPEUTICS, INC. (US) 2012-02-02 US disclosed
US-20110281949-A1 METHODS AND COMPOSITIONS FOR TREATING NEURONAL DAMAGE AND MODULATING TRANSIENT RECEPTOR POTENTIAL CHANNELS MINKE BARUCH (IL) 2011-11-17 US disclosed
US-20110281949-A1 METHODS AND COMPOSITIONS FOR TREATING NEURONAL DAMAGE AND MODULATING TRANSIENT RECEPTOR POTENTIAL CHANNELS MINKE BARUCH (IL) 2011-11-17 US disclosed
WO-2010015965-A2 METHODS AND COMPOSITIONS FOR TREATING NEURONAL DAMAGE AND MODULATING TRANSIENT RECEPTOR POTENTIAL CHANNELS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2010-02-11 WO disclosed
US-4022848-A Bladder composition containing low unsaturation butyl rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203715-A1 USE OF TRP CHANNEL AGONISTS TO TREAT INFECTIONS TRPV1, TRPC4, TRPC3 XDH 2531/4885GABRA1 402/4885GABRB2 397/4885
US-20180093939-A9 NOVEL MONOMERS FROM BIOMASS DCXR, MANBA, PGLS XDH 1936/4885GABRA1 4311/4885GABRB2 3588/4885
US-20130267501-A1 Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof ALDH2, ALDH3A1, ALDH1A1 XDH 54/4885GABRA1 961/4885GABRB2 540/4885
US-20140128827-A1 TRIGGERABLE COMPOSITIONS FOR TWO-STAGE, CONTROLLED RELEASE OF ACTIVE CHEMISTRY BCHE, CEL, ACHE XDH 2345/4885GABRA1 3503/4885GABRB2 2442/4885
US-20110281949-A1 METHODS AND COMPOSITIONS FOR TREATING NEURONAL DAMAGE AND MODULATING TRANSIENT RECEPTOR POTENTIAL CHANNELS TRPV1, TRPM8, TRPC3 XDH 3156/4885GABRA1 350/4885GABRB2 132/4885
US-20170233325-A1 NOVEL MONOMERS FROM BIOMASS DCXR, MANBA, PGLS XDH 1936/4885GABRA1 4311/4885GABRB2 3588/4885
US-20120028907-A1 METHODS FOR IDENTIFICATION OF TUMOR PHENOTYPE AND TREATMENT ERG, ETV1, TP53 XDH 4327/4885GABRA1 3528/4885GABRB2 2148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.