SCHEMBL10014867

SCHEMBL10014867

Cc1c(O)c(O)c(C)c(O)c1O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
SELE P16581 1/20 0.35
ACHE P22303 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
SENP1 Q9P0U3 1/20 0.33
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31
NUAK1 O60285 1/20 0.31
IGF1R P08069 1/20 0.31
MET P08581 1/20 0.31
PIM1 P11309 1/20 0.31
SRC P12931 1/20 0.31
AXL P30530 1/20 0.31
AKT1 P31749 1/20 0.31
KDR P35968 1/20 0.31
NEK2 P51955 1/20 0.31
PLK1 P53350 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559713 0.95 IGF1R (0.35) ALDH1A1SELLSELPSELEACHE
SCHEMBL15676352 0.91 IGF1R (0.33) ALDH1A1SELLSELPSELEACHE
SCHEMBL320898 0.89 ALDH1A1 (0.35) ALDH1A1SELLSELPSELEACHE
SCHEMBL13199249 0.84 IGF1R (0.35) ALDH1A1SELLSELPSELEACHE
SCHEMBL3132042 0.84 LDHA (0.35) ALDH1A1SELLSELPSELEACHE
SCHEMBL70689 0.80 ALOX5 (0.35) ALDH1A1SELLSELPSELEACHE
SCHEMBL2219446 0.80 IGF1R (0.33) ALDH1A1SELLSELPSELEACHE
SCHEMBL21515602 0.80 NUAK1 (0.30) NUAK1IGF1RMETPIM1SRC
SCHEMBL22738821 0.80 CA1 (0.50) ALDH1A1CA1CA2TP53CYP1A2
SCHEMBL21650470 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110523354-B Preparation method of microreactor containing immobilized catalyst 浙江大学 2021-01-19 CN claimed
US-12071503-B2 Method for preparing and repairing covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2024-08-27 US disclosed
EP-3957629-B1 PROCESS FOR MAKING DEUTERATED HYDROXY-BENZBROMARONE AND INTERMEDIATES THEREOF ARTHROSI THERAPEUTICS INC (US) 2023-09-06 EP disclosed
US-20220153904-A1 A METHOD FOR PREPARING AND REPAIRING COVALENT ORGANIC FRAMEWORK MATERIALS ZHEJIANG UNIVERSITY (CN) 2022-05-19 US disclosed
EP-3862341-A1 METHOD FOR PREPARING AND METHOD FOR REPAIRING DEFECTS OF COVALENT ORGANIC FRAMEWORK MATERIAL Zhejiang University (CN) 2021-08-11 EP disclosed
CN-110523354-B Preparation method of microreactor containing immobilized catalyst 浙江大学 2021-01-19 CN disclosed
EP-3305871-B1 USE OF DEUTERATED CARBAZOLE IN ORGANIC ELECTROLUMINESCENT DEVICES UDC IRELAND LTD (IE) 2020-02-26 EP disclosed
EP-3305871-A1 DEUTERATED CARBAZOLE AND ITS USE IN ORGANIC ELECTROLUMINESCENT DEVICES UDC Ireland Limited (IE) 2018-04-11 EP disclosed
EP-1995292-B1 Organic electroluminescent device UDC IRELAND LTD (IE) 2017-11-15 EP disclosed
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. 2015-10-15 US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-8809451-B2 Fluorinated dicarboxylic acid derivative and polymer obtained therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2014-08-19 US disclosed
US-8334384-B2 Process for preparing tetrahydrotetraazapentacenes and derivatives XEROX CORPORATION (US) 2012-12-18 US disclosed
US-8283659-B2 Tetrahydrotetraazapentacenes in thin-film transistors XEROX CORPORATION (US) 2012-10-09 US disclosed
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS XEROX CORPORATION (US) 2012-06-28 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-08 US disclosed
US-4144249-A 2,2,6,6-TETRAMETHYL-BENZOBISDIOXOLE, USEFUL IN PERFUMES S.A. TEXACO BELGIUM N.V. (BE) 1979-03-13 US disclosed
US-4092331-A FROM A POLYHYDRIC PHENOL CONTAINING TWO PAIR ORTHO HYDROXY GROUPS AND A KETONE OR ACETAL, LEWIS ACID CATALYST S.A. TEXACO BELGIUM N.V. (BE) 1978-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS CYP4Z1, TCF4, TERT ALDH1A1 689/4885SELL 3808/4885SELP 4106/4885
US-20120165529-A1 PROCESS FOR PREPARING TETRAHYDROTETRAAZAPENTACENES AND DERIVATIVES DHPS, TBXA2R, DHRS9 ALDH1A1 222/4885SELL 4540/4885SELP 3880/4885
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS PFAS, CHIA, PARN ALDH1A1 1737/4885SELL 514/4885SELP 240/4885
US-20110301305-A1 Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom MCCC2, AFF2, F13A1 ALDH1A1 181/4885SELL 4434/4885SELP 4553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.