SCHEMBL10015050

SCHEMBL10015050

c1ccc(-c2cc(-c3ccccc3)cc(-c3cccc(-c4cccc(-c5cc6c7ccccc7n7c8ccccc8c(c5)c67)c4)c3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
HPGD P15428 3/20 0.38
POLB P06746 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TSPO P30536 1/20 0.38
MAOA P21397 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMO O15229 1/20 0.36
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
HSD17B10 Q99714 2/20 0.36
PLA2G10 O15496 1/20 0.36
TSHR P16473 1/20 0.36
GPR3 P46089 1/20 0.34
ALKBH5 Q6P6C2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015049 1.00 KDM4E (0.38) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL21710635 1.00 KDM4E (0.38) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL10015053 1.00 KDM4E (0.38) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL15460054 0.98 TSPO (0.40) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL15460057 0.98 TSPO (0.40) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL21710687 0.96 KDM4E (0.39) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL16621678 0.95 TSPO (0.44) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL15460165 0.95 TSPO (0.44) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL15460052 0.95 TSPO (0.44) KDM4EHPGDPOLBALDH1A1MEN1
SCHEMBL15460103 0.95 TSPO (0.44) KDM4EHPGDPOLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
EP-4401530-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-07-17 EP disclosed
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 EP disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035614-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
EP-3056504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-08-17 EP disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160233436-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160233436-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-8628864-B2 Indolo[3,2,1-jk]carbazole compound and organic light-emitting device containing the same CANON KABUSHIKI KAISHA (JP) 2014-01-14 US disclosed
US-8628864-B2 Indolo[3,2,1-jk]carbazole compound and organic light-emitting device containing the same CANON KABUSHIKI KAISHA (JP) 2014-01-14 US disclosed
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 US disclosed
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND KDM4E 3586/4885HPGD 1654/4885POLB 1033/4885
US-20160233436-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, OPRD1 KDM4E 2617/4885HPGD 1144/4885POLB 1765/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 KDM4E 3812/4885HPGD 1635/4885POLB 585/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4079/4885HPGD 1173/4885POLB 1008/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP KDM4E 3316/4885HPGD 2623/4885POLB 1485/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 KDM4E 3740/4885HPGD 1314/4885POLB 1650/4885
US-12035614-B2 Organic electroluminescent materials and devices ZFR, SOD1, NDUFS2 KDM4E 3027/4885HPGD 2411/4885POLB 390/4885
US-20120075273-A1 INDOLO[3,2,1-JK]CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME HTR3D, SYMPK, NLK KDM4E 2644/4885HPGD 1221/4885POLB 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.