Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.49 |
| ▸ | TLR6 | Q9Y2C9 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730839 | 0.96 | KDM4E (0.53) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL480276 | 0.82 | KDM4E (0.59) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL30463054 | 0.82 | KDM4E (0.59) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| Potassium Ion SCHEMBL29026645 | 0.82 | CTSD (0.56) | MAPTALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL29360359 | 0.81 | MAPT (0.59) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL29502905 | 0.81 | LMNA (0.57) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL312140 | 0.81 | LMNA (0.57) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL2066210 | 0.81 | KDM4E (0.57) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL22588880 | 0.81 | KDM4E (0.57) | KDM4EMAPTALDH1A1ALOX15MAPK1 | |
| SCHEMBL5458 | 0.81 | MAPT (0.59) | KDM4EMAPTALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119488463-A | Double-layer essential oil with antioxidant and tightening effects and preparation method thereof | 广州柏薇生物科技有限公司 | 2025-02-21 | — | — | CN | claimed |
| CN-118975952-A | Organic acid temperature-sensitive gel and preparation method and application thereof | 诺斯贝尔化妆品股份有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118512372-A | Whitening and freckle-removing emulsion and preparation method thereof | 广州宝莱生物科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| CN-118252781-A | A method for preparing skin caring liquid containing marine organism extract | 苏州花时南浦生物科技有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-118121526-A | Essence composition and application thereof in rapid wrinkle resistance and hydroglabrous muscle building | 广州宝莱生物科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-113893818-B | Surface-modified zeolite, agilawood essential oil for slimming, extraction method and application | 广州东智盟化妆品有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117180153-B | Whitening composition and preparation method and application thereof | 广州维特丝化妆品有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117695169-A | Liposome containing strong electrolyte skin care functional component and preparation method thereof | 杭州睿研前瞻生物科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117180153-A | Whitening composition and preparation method and application thereof | 广州研柔慕化妆品有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117084954-A | Whitening and freckle-removing essence and preparation method thereof | 言颜信息科技(上海)有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-111419755-A | Agilawood fullerene essence and preparation method thereof | 海口楠脂香业有限公司 | 2020-07-17 | — | — | CN | claimed |
| CN-111388369-A | Agilawood skin moisturizing lotion and preparation method thereof | 海口楠脂香业有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-111281840-A | Skin brightening and beautifying cream and preparation method thereof | 广州伊尔美生物科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-110448482-B | Emulsion and preparation method thereof | 瑞希(重庆)生物科技有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-111228139-A | Whitening and moisturizing skin care product | 深圳市百吉因生物科技有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111150699-A | Brightening and moistening beauty cream | 广州伊尔美生物科技有限公司 | 2020-05-15 | — | — | CN | claimed |
| CN-107374988-B | Preparation method of nonionic vesicle with whitening effect | 珀莱雅化妆品股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110755348-A | Skin care composition and preparation method thereof | 邹杰 | 2020-02-07 | — | — | CN | claimed |
| CN-110638666-A | W/O/W type multiple emulsion and preparation method thereof | 瑞希(重庆)生物科技有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-110538080-A | Microemulsion and preparation method thereof | RUIXI CHONGQING BIOLOGICAL TECH CO LTD | 2019-12-06 | — | — | CN | claimed |