SCHEMBL316521

SCHEMBL316521

C=Cc1ccc(COCCCCCCOc2ccc3c(c2)C(=O)N([C@@H](Cc2ccccc2)C(=O)O)C3=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.49
▸ GAA P10253 1/20 0.49
▸ KMT2A Q03164 4/20 0.48
▸ POLB P06746 2/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ CYP2D6 P10635 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ BCL2 P10415 3/20 0.46
▸ BCL2L2 Q92843 3/20 0.46
▸ BAD Q92934 3/20 0.46
▸ AADAT Q8N5Z0 1/20 0.46
▸ TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL316517 0.84 L3MBTL1 (0.38) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL10037556 0.81 L3MBTL1 (0.37) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL316509 0.78 L3MBTL1 (0.35) L3MBTL1ALDH1A1GAAKMT2AMEN1
SCHEMBL4481252 0.75 ALDH1A1 (0.74) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL13919544 0.75 ALDH1A1 (0.74) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL2267205 0.71 TDP1 (0.46) L3MBTL1ALDH1A1TDP1TSHR
SCHEMBL6307495 0.71 POLB (0.60) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL6307483 0.71 POLB (0.60) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL478614 0.69 ALDH1A1 (1.00) L3MBTL1ALDH1A1GAAKMT2APOLB
SCHEMBL4861809 0.69 ALDH1A1 (1.00) L3MBTL1ALDH1A1GAAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2045014-B1 POLYMER-SUPPORTED METAL COMPLEX CATALYST UNIV HOKKAIDO NAT UNIV CORP (JP) 2014-01-15 — — EP disclosed
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 — — US disclosed
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-09-10 — — US disclosed
EP-2045014-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST National University Corporation Hokkaido University (JP) 2009-04-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST PYM1, ARG1, SCO2 L3MBTL1 2735/4885ALDH1A1 2736/4885GAA 4499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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