SCHEMBL10041652

SCHEMBL10041652

CC1(C)OB(c2ccccc2Cl)OC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.46
LIPG Q9Y5X9 12/20 0.46
JAK2 O60674 1/20 0.41
BTK Q06187 1/20 0.41
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
P4HB P07237 1/20 0.33
P2RX7 Q99572 1/20 0.33
ANPEP P15144 1/20 0.33
LAP3 P28838 1/20 0.33
LIPE Q05469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470922 0.85 LPL (0.41) LPLLIPGJAK2BTK
SCHEMBL25226735 0.85 LPL (0.41) LPLLIPGJAK2BTK
SCHEMBL5899734 0.84 LPL (0.54) LPLLIPGP4HBP2RX7ANPEP
SCHEMBL746647 0.84 JAK2 (0.42) LPLLIPGJAK2BTKLMNA
SCHEMBL30550009 0.84 JAK2 (0.42) LPLLIPGJAK2BTKLMNA
SCHEMBL16815466 0.82 JAK2 (0.53) LPLLIPGJAK2BTKP2RX7
SCHEMBL22208077 0.81 JAK2 (0.41) LPLLIPGJAK2BTKTSHR
SCHEMBL29634795 0.81 JAK2 (0.41) LPLLIPGJAK2BTKTSHR
SCHEMBL23045909 0.81 JAK2 (0.41) LPLLIPGJAK2BTK
SCHEMBL15649181 0.81 JAK2 (0.41) LPLLIPGJAK2BTKTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042748-A1 AZETIDINE COMPOUNDS FOR TREATMENT OF HSV ASSEMBLY BIOSCIENCES INC (US) 2026-02-12 US disclosed
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-20 US disclosed
US-12410183-B2 Sars-cov2 main protease inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
CN-119894869-A Substituted biaryl kadetoxin-like quinolones having enhanced antiparasitic activity 俄勒冈健康与科学大学 2025-04-25 CN disclosed
EP-4536639-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY Oregon Health & Science University (US) 2025-04-16 EP disclosed
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-04-10 US disclosed
US-20250059188-A1 ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-02-20 US disclosed
WO-2025033037-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2025-02-13 WO disclosed
US-20250042915-A1 SARS-COV2 MAIN PROTEASE INHIBITORS GILEAD SCIENCES, INC. 2025-02-06 US disclosed
US-12187742-B2 Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy XRAD THERAPEUTICS, INC. (US) 2025-01-07 US disclosed
US-9012651-B2 TRPV3 modulators ABBVIE INC. (US) 2015-04-21 US disclosed
WO-2014009169-A1 NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS UNIVERSITE DE BORDEAUX 1 (FR) 2014-01-16 WO disclosed
WO-2014009169-A1 NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS UNIVERSITE DE BORDEAUX 1 (FR) 2014-01-16 WO disclosed
EP-2684887-A1 New process for preparing arylboranes by arylation of organoboron compounds UNIVERSITE DE BORDEAUX I (FR) 2014-01-15 EP disclosed
EP-2684887-A1 New process for preparing arylboranes by arylation of organoboron compounds UNIVERSITE DE BORDEAUX I (FR) 2014-01-15 EP disclosed
US-8368062-B2 Nitrogen-containing heterocyclic compound and organic electronic device using the same LG CHEM, LTD. (KR) 2013-02-05 US disclosed
WO-2012129491-A1 TRPV3 MODULATORS ABBOTT LABORATORIES (US) 2012-09-27 WO disclosed
US-20120245124-A1 TRPV3 Modulators ABBOTT LABORATORIES (US) 2012-09-27 US disclosed
US-20120007069-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2012-01-12 US disclosed
US-20110127513-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042915-A1 SARS-COV2 MAIN PROTEASE INHIBITORS ACE2, TMPRSS2, ACE LPL 230/4885LIPG 232/4885JAK2 1797/4885
US-20250353828-A1 SUBSTITUTED BIARYL ENDOCHIN-LIKE QUINOLONES WITH ENHANCED ANTIPARASITIC ACTIVITY EPX, TFEB, EPHX1 LPL 1736/4885LIPG 724/4885JAK2 1417/4885
US-20120007069-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, VDAC3 LPL 4810/4885LIPG 3725/4885JAK2 3325/4885
US-20120245124-A1 TRPV3 Modulators TRPV3, TRPV2, TRPV1 LPL 3028/4885LIPG 3200/4885JAK2 1620/4885
US-20250115598-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 LPL 1442/4885LIPG 1293/4885JAK2 1688/4885
US-12410183-B2 Sars-cov2 main protease inhibitors ACE2, TMPRSS2, ACE LPL 230/4885LIPG 232/4885JAK2 1797/4885
US-20110127513-A1 NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME VDAC2, VDAC1, VDAC3 LPL 4810/4885LIPG 3725/4885JAK2 3325/4885
US-20260042748-A1 AZETIDINE COMPOUNDS FOR TREATMENT OF HSV CXCR1, ZC3HAV1L, ZC3HAV1 LPL 1091/4885LIPG 1470/4885JAK2 1993/4885
US-12187742-B2 Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy ATM, CHEK2, CHEK1 LPL 2944/4885LIPG 2120/4885JAK2 925/4885
US-20250059188-A1 ARYLSULPHONAMIDE COMPOUNDS MLKL, CASP1, CASP9 LPL 1381/4885LIPG 1144/4885JAK2 807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.