SCHEMBL10045907

SCHEMBL10045907

Oc1ccc(P2(=S)SP(=S)(c3ccc(O)cc3)S2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
TYR P14679 2/20 0.42
CA3 P07451 2/20 0.42
CYP3A4 P08684 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CA14 Q9ULX7 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
CA12 O43570 1/20 0.42
GMNN O75496 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HPGD P15428 1/20 0.42
NFKB1 P19838 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15932418 0.89 ACHE (0.54) ALOX15ALDH1A1LMNATYRCA3
SCHEMBL17369684 0.85 LMNA (0.61) ALOX15ALDH1A1LMNATYRCYP3A4
SCHEMBL10077999 0.84 ESR2 (0.53) ALDH1A1LMNACA14KDM4EMAPT
SCHEMBL12601021 0.78 LMNA (0.46) ALDH1A1LMNACYP3A4HSD17B10KDM4E
SCHEMBL15932386 0.77 ACHE (0.45) ALOX15ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL10045868 0.76 KDM4E (0.41) ALDH1A1LMNAHSD17B10KDM4EMAPT
Hydroquinone SCHEMBL460669 0.65 ALOX15 (1.00) ALOX15ALDH1A1LMNATYRCA3
Hydroquinone SCHEMBL15516 0.65
Hydroquinone SCHEMBL11511669 0.65 ALOX15 (1.00) ALOX15ALDH1A1LMNATYRCA3
Hydroquinone SCHEMBL10550177 0.62 CA3 (0.73) ALOX15ALDH1A1LMNATYRCA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114858-B2 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2012-02-14 US disclosed
US-8114857-B2 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2012-02-14 US disclosed
US-8114858-B2 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2012-02-14 US disclosed
US-8114857-B2 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2012-02-14 US disclosed
WO-2011082234-A1 THIONATED AROMATIC BISIMIDES AS ORGANIC SEMICONDUCTORS AND DEVICES INCORPORATING THEM POLYERA CORPORATION (US) 2011-07-07 WO disclosed
EP-1883645-B1 DERIVATIVES OF 4-OR 5-AMINOSALICYLIC ACID ANTIBE THERAPEUTICS INC (CA) 2011-06-29 EP disclosed
US-20110130368-A1 DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID ANTIBE THERAPEUTICS INC. (CA) 2011-06-02 US disclosed
US-20110130368-A1 DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID ANTIBE THERAPEUTICS INC. (CA) 2011-06-02 US disclosed
US-20110098257-A1 DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID ANTIBE THERAPEUTICS INC. (CA) 2011-04-28 US disclosed
US-20110098257-A1 DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID ANTIBE THERAPEUTICS INC. (CA) 2011-04-28 US disclosed
US-7498355-B2 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2009-03-03 US disclosed
US-7488786-B2 emulsion polymerization process for producing a polymer by controlled polymerization which comprises polymerizing at least one monomer in the presence of a free radical control agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-02-10 US disclosed
US-7462674-B2 Oxathiazaphospholidine free radical control agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-12-09 US disclosed
US-20080207564-A1 Derivaitves of 4-Or 5-Aminosalicylic Acid ANTIBE THERAPEUTICS INC. (CA) 2008-08-28 US disclosed
US-20080207564-A1 Derivaitves of 4-Or 5-Aminosalicylic Acid ANTIBE THERAPEUTICS INC. (CA) 2008-08-28 US disclosed
US-20080097057-A1 Oxathiazaphospholidine free radical control agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-04-24 US disclosed
US-7345186-B2 Oxathiazaphospholidine free radical control agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-03-18 US disclosed
US-20080033197-A1 Oxathiazaphospholidine free radical control agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-02-07 US disclosed
US-20070197479-A1 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2007-08-23 US disclosed
US-20070197479-A1 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110098257-A1 DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID CBS, SI, APC ALOX15 98/4885ALDH1A1 572/4885LMNA 4653/4885
US-20080207564-A1 Derivaitves of 4-Or 5-Aminosalicylic Acid CBS, SI, TST ALOX15 203/4885ALDH1A1 388/4885LMNA 4721/4885
US-20110130368-A1 DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID CBS, SI, APC ALOX15 98/4885ALDH1A1 572/4885LMNA 4653/4885
US-20080033197-A1 Oxathiazaphospholidine free radical control agent NOX4, AR, AHR ALOX15 265/4885ALDH1A1 281/4885LMNA 1391/4885
US-20070197479-A1 Derivatives of 4- or 5-aminosalicylic acid CBS, SI, APC ALOX15 98/4885ALDH1A1 572/4885LMNA 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.