Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069593 | 0.93 | MEN1 (0.35) | HPDMAPK14MC4R | |
| SCHEMBL10069626 | 0.92 | HPD (0.34) | HPDMAPK14 | |
| SCHEMBL10069624 | 0.86 | GHSR (0.33) | HPDMAPK14 | |
| SCHEMBL10069607 | 0.83 | ADORA2A (0.35) | HPDMAPK14 | |
| SCHEMBL10069609 | 0.83 | LMNA (0.34) | HPDMAPK14 | |
| SCHEMBL10069598 | 0.82 | TP53 (0.33) | MAPK14 | |
| SCHEMBL10069618 | 0.82 | PTGER1 (0.35) | HPDMAPK14 | |
| SCHEMBL10069605 | 0.77 | CNR1 (0.34) | — | |
| SCHEMBL10069596 | 0.77 | MAPT (0.36) | MAPK14 | |
| SCHEMBL10069629 | 0.74 | RGS4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |