Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069624 | 0.87 | GHSR (0.33) | PTGER1AKR1C3AKR1C2MAPK14CYP1A2 | |
| SCHEMBL10069599 | 0.84 | PTGS2 (0.34) | PTGER1AKR1C3AKR1C2PTGS1MEN1 | |
| SCHEMBL10069626 | 0.83 | HPD (0.34) | PTGER1MAPK14CYP1A2CYP2C9TBXA2R | |
| SCHEMBL10069593 | 0.82 | MEN1 (0.35) | MAPK14MEN1KMT2AHPD | |
| SCHEMBL10069608 | 0.82 | HPD (0.32) | MAPK14HPD | |
| SCHEMBL10069609 | 0.81 | LMNA (0.34) | MAPK14MEN1KMT2AMAPK1HPD | |
| SCHEMBL10069607 | 0.81 | ADORA2A (0.35) | MAPK14HPD | |
| SCHEMBL10069594 | 0.71 | MAPT (0.38) | CYP1A2KDM4E | |
| SCHEMBL10069596 | 0.70 | MAPT (0.36) | MAPK14CYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL10069590 | 0.67 | ALDH1A1 (0.39) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |