Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.64 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346392 | 0.87 | GSTO1 (0.50) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL5773831 | 0.86 | GSTO1 (0.47) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL5773112 | 0.82 | ALOX5 (0.57) | ALOX5MEN1KMT2ANR1I2 | |
| SCHEMBL10074174 | 0.82 | PSEN1 (0.70) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL13086409 | 0.82 | PSEN1 (0.70) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL627629 | 0.82 | PSEN1 (0.70) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL3243733 | 0.82 | PSEN1 (0.70) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL3243972 | 0.82 | PSEN1 (0.70) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL9280072 | 0.81 | PSEN1 (0.52) | PSEN1GSTO1PTPN1ALOX5MEN1 | |
| SCHEMBL14580953 | 0.81 | GSTO1 (0.44) | PSEN1GSTO1PTPN1ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | SANDERS BOB G (US) | 2012-10-04 | — | — | US | disclosed |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | SANDERS BOB G (US) | 2012-10-04 | — | — | US | disclosed |
| US-8148424-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148424-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2010-12-02 | — | — | US | disclosed |
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2010-12-02 | — | — | US | disclosed |
| US-7718814-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718814-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-7608638-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-7608638-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2008-05-22 | — | — | US | disclosed |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2008-05-22 | — | — | US | disclosed |
| US-7312232-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312232-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-7300954-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300954-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TST, TXNRD3, TXNRD1 | PSEN1 3935/4885GSTO1 40/4885PTPN1 2856/4885 |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TST, TXNRD3, TXNRD1 | PSEN1 3869/4885GSTO1 35/4885PTPN1 2806/4885 |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TXN, TXN2, TTPA | PSEN1 2772/4885GSTO1 13/4885PTPN1 2453/4885 |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | TST, TXNRD3, TXNRD1 | PSEN1 3935/4885GSTO1 40/4885PTPN1 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.