Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411810 | 0.90 | ALDH1A1 (0.51) | BRD4ALDH1A1MAPTKDM4ERAD51 | |
| SCHEMBL7773324 | 0.80 | NPC1 (0.59) | BRD4ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8021163 | 0.77 | ELANE (0.51) | ALDH1A1MAPTKDM4ECYP1A2POLB | |
| SCHEMBL9147984 | 0.77 | BRD4 (0.55) | BRD4ALDH1A1MAPTKDM4ERAD51 | |
| SCHEMBL1080719 | 0.77 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL15146078 | 0.76 | ROCK2 (0.67) | BRD4ALDH1A1MAPT | |
| SCHEMBL1247686 | 0.76 | ROCK2 (0.55) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1156215 | 0.76 | PEPD (0.42) | ALDH1A1MAPTKMT2AMEN1GFER | |
| SCHEMBL9172845 | 0.75 | ROCK2 (0.54) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL14360693 | 0.75 | CA2 (0.46) | ALDH1A1MAPTKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044052-B2 | Inhibitors of fatty acid amide hydrolase; N-pyridin-3-yl-4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzylidene)piperidine-1-carboxamide; elevate brain anandamide levels; pain, urinary incontinence, cognitive disorders, anxiety, depression, sleeping, eating, movement disorders, glaucoma, psoriasis | PFIZER INC. (US) | 2011-10-25 | — | — | US | disclosed |
| EP-2076508-B1 | BIARYL ETHER UREA COMPOUNDS | PFIZER PROD INC (US) | 2011-01-05 | — | — | EP | disclosed |
| US-20080261941-A1 | Biaryl Ether Urea Compounds | Jazz Pharmaceuticals Therapeutics, Inc. | 2008-10-23 | — | — | US | disclosed |
| US-5888694-A | MATERIAL CONTAINING COMPOUND HAVING ADSORPTION ACCELERATING GROUP AND QUATERNIZED NITROGEN-CONTAINING HETEROCYCLIC RING;FORMING HIGH CONTRAST IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0267598-B1 | Superhigh contrast negative-type silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1995-02-08 | — | — | EP | disclosed |
| US-5192647-A | Forming latent images | FUJI PHOTO FILM CO., LTD. (JP) | 1993-03-09 | — | — | US | disclosed |
| US-4851321-A | HYDRAZINE DERIVATIVE, HETEROCYCLIC CONTRAST ENHANCER | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0267598-A2 | Superhigh contrast negative-type silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261941-A1 | Biaryl Ether Urea Compounds | FAAH, FAAH2, LIPC | BRD4 273/4885ALDH1A1 360/4885MAPT 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.