SCHEMBL10135949

SCHEMBL10135949

c1ccc(-c2ccc(-c3ccc(N(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccc(N(c6ccccc6)c6cccc7ccccc67)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.44
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
APP P05067 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
MEN1 O00255 1/20 0.34
CRHBP P24387 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14018321 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL14069693 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL10135947 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL13854468 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL12280969 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL13854489 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL804913 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL17930281 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL22876538 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4
SCHEMBL13854480 1.00 SIGMAR1 (0.44) SIGMAR1ALDH1A1L3MBTL1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3605638-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2023-11-08 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-11158813-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-11063223-B2 Organic electron transport material and organic electroluminescent element using same DYDEN CORPORATION (JP) 2021-07-13 US disclosed
US-20210143326-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2021-05-13 US disclosed
US-10892420-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-01-12 US disclosed
EP-3010068-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2020-12-09 EP disclosed
US-10693078-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-06-23 US disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10566540-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-18 US disclosed
US-20120302793-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. 2012-11-29 US disclosed
US-20120302793-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. 2012-11-29 US disclosed
US-20120228594-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-09-13 US disclosed
US-20120228594-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-09-13 US disclosed
US-20120184776-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120184776-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 SIGMAR1 1676/4885ALDH1A1 228/4885L3MBTL1 2392/4885
US-11158813-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNH3 SIGMAR1 2674/4885ALDH1A1 489/4885L3MBTL1 348/4885
US-10693078-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNH3 SIGMAR1 2100/4885ALDH1A1 579/4885L3MBTL1 1378/4885
US-11063223-B2 Organic electron transport material and organic electroluminescent element using same SLCO2A1, SLCO4C1, SLCO2B1 SIGMAR1 327/4885ALDH1A1 1391/4885L3MBTL1 1440/4885
US-20120184776-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, DDC, ALKBH2 SIGMAR1 2116/4885ALDH1A1 578/4885L3MBTL1 1286/4885
US-20120302793-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME NAT1, AFF1, AOC2 SIGMAR1 468/4885ALDH1A1 103/4885L3MBTL1 1935/4885
US-10566540-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNN1 SIGMAR1 1544/4885ALDH1A1 459/4885L3MBTL1 1105/4885
US-10892420-B2 Organic electroluminescent device SLC7A5, KCNN2, SLC43A1 SIGMAR1 1874/4885ALDH1A1 396/4885L3MBTL1 655/4885
US-20120112176-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME EML4, DDC, ALKBH2 SIGMAR1 2138/4885ALDH1A1 645/4885L3MBTL1 1137/4885
US-20080303417-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same DDC, AOC2, ALKBH2 SIGMAR1 1483/4885ALDH1A1 238/4885L3MBTL1 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.