Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4181830 | 0.98 | KDM4E (0.68) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL16595811 | 0.87 | PTGS1 (0.57) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL1583201 | 0.84 | PTGS1 (0.66) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL31000249 | 0.84 | RAB9A (0.53) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL1445451 | 0.82 | KDM4E (1.00) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL8609187 | 0.82 | RAB9A (0.53) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL1311917 | 0.81 | KDM4E (0.52) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL871014 | 0.81 | KDM4E (0.69) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL3035991 | 0.81 | PTGS1 (0.66) | KDM4EPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL7269185 | 0.81 | KDM4E (0.78) | KDM4EPOLBRAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239594-B | 6- (imidazo [1,2-a ] pyridin-6-yl) quinazoline derivatives and uses thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-09-22 | — | — | CN | claimed |
| CN-116239594-A | 6- (imidazo [1,2-a ] pyridin-6-yl) quinazoline derivatives and uses thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-06-09 | — | — | CN | claimed |
| CN-112573978-B | High-efficiency halogenation synthesis method of aryl halide | 北京大学 | 2022-05-13 | — | — | CN | claimed |
| US-8288424-B2 | Substituted tetrahydroimidazopyridine compounds and the use thereof in the treatment of pain and other conditions | GRUENENTHAL GMBH (DE) | 2012-10-16 | — | — | US | claimed |
| EP-2235013-B1 | SUBSTITUTED TETRAHYDROIMIDAZOPYRIDINE COMPOUNDS AND THE USE THEREOF IN PHARMACEUTICALS | GRUENENTHAL GMBH (DE) | 2012-08-01 | — | — | EP | claimed |
| US-20090186902-A1 | Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2009-07-23 | — | — | US | claimed |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HAGER BIOSCIENCES, LLC (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260047580-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2026-02-19 | — | — | US | disclosed |
| US-20250388577-A1 | METTL3 INHIBITORY COMPOUNDS | STORM THERAPEUTICS LTD (GB) | 2025-12-25 | — | — | US | disclosed |
| US-12478067-B2 | Heterocyclic compound and harmful arthropod pest control composition containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-11-25 | — | — | US | disclosed |
| US-12473303-B2 | 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino methyl]piperidin-3-ol compounds and their therapeutic use | Carrick Therapeutics Limited (IE) | 2025-11-18 | — | — | US | disclosed |
| US-12358915-B2 | METTL3 inhibitory compounds | STORM Therapeutics Ltd. (GB) | 2025-07-15 | — | — | US | disclosed |
| CN-114929708-B | 4- [ [ (7-Aminopyrazolo [1,5-a ] pyrimidin-5-yl) amino ] methyl ] piperidin-3-ol compounds and their therapeutic uses | 卡里克治疗有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0499521-B1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0238070-B1 | Sulfonylurea compounds, their production and herbicidal use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5266576-A | Anticarcinogenic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | disclosed |
| EP-0238070-A2 | Sulfonylurea compounds, their production and herbicidal use | Takeda Chemical Industries, Ltd. (JP) | 1987-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358915-B2 | METTL3 inhibitory compounds | METTL3, METTL16, DIMT1 | KDM4E 62/4885POLB 1183/4885RAB9A 1839/4885 |
| US-20250388577-A1 | METTL3 INHIBITORY COMPOUNDS | METTL3, RNMT, TPMT | KDM4E 717/4885POLB 1361/4885RAB9A 1986/4885 |
| US-12473303-B2 | 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino methyl]piperidin-3-ol compounds and their therapeutic use | CDK3, CDK1, CDK2 | KDM4E 1437/4885POLB 110/4885RAB9A 2959/4885 |
| US-20090186902-A1 | Substituted Tetrahydroimidazopyridine Compounds and the Use Thereof in the Treatment of Pain and Other Conditions | HRH4, TRPV1, QDPR | KDM4E 1006/4885POLB 3927/4885RAB9A 1304/4885 |
| US-12478067-B2 | Heterocyclic compound and harmful arthropod pest control composition containing same | C5, COX6C, C1S | KDM4E 1825/4885POLB 3673/4885RAB9A 665/4885 |
| US-20260047580-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME | COX6C, COX6B1, CYC1 | KDM4E 2265/4885POLB 3857/4885RAB9A 269/4885 |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | OPRK1, OPRD1, HCRTR2 | KDM4E 2137/4885POLB 3944/4885RAB9A 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.