Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345768 | 0.85 | HPGD (0.51) | MAPTHPGDRAB9AGAASMN1; SMN2 | |
| SCHEMBL10187010 | 0.82 | CYP1A2 (0.42) | MAPTHPGDRAB9AGAASMN1; SMN2 | |
| SCHEMBL12914773 | 0.81 | KCNN4 (0.50) | MAPTHPGDRAB9AGAASMN1; SMN2 | |
| SCHEMBL12286073 | 0.78 | ALOX5 (0.51) | MAPTHPGDRAB9AGAASMN1; SMN2 | |
| SCHEMBL26292979 | 0.77 | APAF1 (0.42) | MAPTHPGDRAB9AGAALMNA | |
| SCHEMBL12038615 | 0.77 | APAF1 (0.42) | MAPTHPGDRAB9AGAALMNA | |
| SCHEMBL28777735 | 0.77 | KCNN4 (0.41) | HTTCYP2C19HIF1AHDAC3HDAC4 | |
| SCHEMBL8083085 | 0.77 | PTPN1 (0.42) | MAPTHPGDSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL7923982 | 0.77 | KCNN4 (0.41) | MAPTCYP2C19HIF1AHDAC3HDAC4 | |
| SCHEMBL31370489 | 0.77 | CYP1A2 (0.58) | MAPTCYP1A2CYP3A4RECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234912-A1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | APICAL MOLECULAR BIOTECH CO., LTD. (TW) | 2023-07-27 | — | — | US | disclosed |
| US-20170087205-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | PALATIN TECHNOLOGIES INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160354443-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | PALATIN TECHNOLOGIES INC (US) | 2016-12-08 | — | — | US | disclosed |
| US-8828926-B2 | Uses of natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-8580746-B2 | Amide linkage cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580747-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130274207-A9 | Uses of Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130045928-A1 | Uses of Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20130045928-A1 | Uses of Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-8114844-B2 | Linear and cyclic melanocortin receptor-specific peptidomimetics | PALATIN TECHNOLOGIES, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110263818-A1 | Peptidic Constructs with Amino Acid Surrogates | PALATIN TECHNOLOGIES, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-7964181-B2 | Amino acid surrogates for peptidic constructs | PALATIN TECHNOLOGIES, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-7795221-B2 | Linear natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100075895-A1 | Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100035821-A1 | Amide Linkage Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-02-11 | — | — | US | disclosed |
| US-7622440-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090069224-A1 | Linear and Cyclic Melanocortin Receptor-Specific Peptidomimetics | PALATIN TECHNOLOGIES, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20070265206-A1 | Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070260040-A1 | Amino Acid Surrogates for Peptidic Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2007-11-08 | — | — | US | disclosed |
| US-20070232546-A1 | Linear Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263818-A1 | Peptidic Constructs with Amino Acid Surrogates | ARGLU1, QRFPR, ARG1 | MAPT 3802/4885HPGD 4687/4885RAB9A 1305/4885 |
| US-20070265206-A1 | Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | MAPT 4865/4885HPGD 1727/4885RAB9A 2646/4885 |
| US-20070260040-A1 | Amino Acid Surrogates for Peptidic Constructs | ARGLU1, ARG1, QRFPR | MAPT 4163/4885HPGD 3235/4885RAB9A 1376/4885 |
| US-20130045928-A1 | Uses of Natriuretic Peptide Constructs | NPR1, NPPA, NPR3 | MAPT 4768/4885HPGD 987/4885RAB9A 3643/4885 |
| US-20170087205-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | NPR1, NPR3, NPPA | MAPT 4826/4885HPGD 2862/4885RAB9A 1642/4885 |
| US-20230234912-A1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | FABP1, GLS2, SLC1A5 | MAPT 2142/4885HPGD 793/4885RAB9A 2196/4885 |
| US-20090069224-A1 | Linear and Cyclic Melanocortin Receptor-Specific Peptidomimetics | MC1R, MC3R, MC5R | MAPT 2951/4885HPGD 3779/4885RAB9A 1219/4885 |
| US-20100035821-A1 | Amide Linkage Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | MAPT 4688/4885HPGD 1802/4885RAB9A 2369/4885 |
| US-20070232546-A1 | Linear Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | MAPT 4828/4885HPGD 1617/4885RAB9A 2902/4885 |
| US-20100075895-A1 | Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | MAPT 4865/4885HPGD 1727/4885RAB9A 2646/4885 |
| US-20130274207-A9 | Uses of Natriuretic Peptide Constructs | NPR1, NPPA, NPR3 | MAPT 4768/4885HPGD 987/4885RAB9A 3643/4885 |
| US-20160354443-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | NPR1, NPR3, NPPA | MAPT 4826/4885HPGD 2862/4885RAB9A 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.