Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629286 | 0.85 | KCNN4 (0.41) | CYP1A2CYP3A4RECQLCYP2C19HIF1A | |
| SCHEMBL28769203 | 0.84 | CYP1A2 (0.41) | CYP1A2CYP3A4RECQLCYP2C19HIF1A | |
| SCHEMBL12286073 | 0.82 | ALOX5 (0.51) | CYP3A4RECQLCYP2C19MAPK1KCNN4 | |
| SCHEMBL10187008 | 0.82 | MAPT (0.51) | CYP1A2CYP3A4RECQLCYP2C19HIF1A | |
| SCHEMBL29872151 | 0.80 | L3MBTL1 (0.49) | CYP1A2CYP2C19HIF1APOLBMAPT | |
| SCHEMBL30564476 | 0.80 | KIF11 (0.50) | CYP1A2CYP3A4RECQLMAPK1KCNN4 | |
| SCHEMBL14401408 | 0.79 | ALDH1A1 (0.53) | KCNN4POLBKMT2AHTT | |
| SCHEMBL12914773 | 0.78 | KCNN4 (0.50) | CYP1A2CYP3A4RECQLCYP2C19HIF1A | |
| SCHEMBL27548806 | 0.78 | KCNN4 (0.41) | CYP1A2CYP3A4RECQLCYP2C19HIF1A | |
| SCHEMBL16576419 | 0.78 | KDM4E (0.47) | CYP1A2RECQLCYP2C19MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234912-A1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | APICAL MOLECULAR BIOTECH CO., LTD. (TW) | 2023-07-27 | — | — | US | disclosed |
| US-20170087205-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | PALATIN TECHNOLOGIES INC (US) | 2017-03-30 | — | — | US | disclosed |
| US-20160354443-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | PALATIN TECHNOLOGIES INC (US) | 2016-12-08 | — | — | US | disclosed |
| US-8828926-B2 | Uses of natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-8580746-B2 | Amide linkage cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580747-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130274207-A9 | Uses of Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130045928-A1 | Uses of Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-8114844-B2 | Linear and cyclic melanocortin receptor-specific peptidomimetics | PALATIN TECHNOLOGIES, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110263818-A1 | Peptidic Constructs with Amino Acid Surrogates | PALATIN TECHNOLOGIES, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-7964181-B2 | Amino acid surrogates for peptidic constructs | PALATIN TECHNOLOGIES, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-7795221-B2 | Linear natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100075895-A1 | Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-20100035821-A1 | Amide Linkage Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2010-02-11 | — | — | US | disclosed |
| US-7622440-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20090069224-A1 | Linear and Cyclic Melanocortin Receptor-Specific Peptidomimetics | PALATIN TECHNOLOGIES, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-20070265206-A1 | Cyclic Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070260040-A1 | Amino Acid Surrogates for Peptidic Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2007-11-08 | — | — | US | disclosed |
| US-20070232546-A1 | Linear Natriuretic Peptide Constructs | PALATIN TECHNOLOGIES, INC. (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263818-A1 | Peptidic Constructs with Amino Acid Surrogates | ARGLU1, QRFPR, ARG1 | CYP1A2 4184/4885CYP3A4 4781/4885RECQL 2110/4885 |
| US-20070265206-A1 | Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | CYP1A2 4685/4885CYP3A4 4828/4885RECQL 751/4885 |
| US-20070260040-A1 | Amino Acid Surrogates for Peptidic Constructs | ARGLU1, ARG1, QRFPR | CYP1A2 1546/4885CYP3A4 3164/4885RECQL 1453/4885 |
| US-20130045928-A1 | Uses of Natriuretic Peptide Constructs | NPR1, NPPA, NPR3 | CYP1A2 3935/4885CYP3A4 4608/4885RECQL 1313/4885 |
| US-20170087205-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | NPR1, NPR3, NPPA | CYP1A2 4718/4885CYP3A4 4883/4885RECQL 460/4885 |
| US-20230234912-A1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | FABP1, GLS2, SLC1A5 | CYP1A2 1961/4885CYP3A4 1595/4885RECQL 4868/4885 |
| US-20090069224-A1 | Linear and Cyclic Melanocortin Receptor-Specific Peptidomimetics | MC1R, MC3R, MC5R | CYP1A2 3112/4885CYP3A4 4425/4885RECQL 2246/4885 |
| US-20100035821-A1 | Amide Linkage Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | CYP1A2 4813/4885CYP3A4 4877/4885RECQL 1531/4885 |
| US-20070232546-A1 | Linear Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | CYP1A2 4330/4885CYP3A4 4628/4885RECQL 1008/4885 |
| US-20100075895-A1 | Cyclic Natriuretic Peptide Constructs | NPR1, NPR3, NPPA | CYP1A2 4685/4885CYP3A4 4828/4885RECQL 751/4885 |
| US-20130274207-A9 | Uses of Natriuretic Peptide Constructs | NPR1, NPPA, NPR3 | CYP1A2 3935/4885CYP3A4 4608/4885RECQL 1313/4885 |
| US-20160354443-A1 | Replacement Therapy for Natriuretic Peptide Deficiencies | NPR1, NPR3, NPPA | CYP1A2 4718/4885CYP3A4 4883/4885RECQL 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.