SCHEMBL10191090

SCHEMBL10191090

C#CCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PARL Q9H300 1/20 0.32
MGLL Q99685 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138410 0.83 PSMB8 (0.31)
SCHEMBL213096 0.82 ALDH1A1 (0.35) MGLL
SCHEMBL1700762 0.80 CYP1A2 (0.35)
SCHEMBL1981540 0.79 CYP1A2 (0.42)
SCHEMBL43576 0.79 PSMB8 (0.35) PARLMGLL
SCHEMBL2618714 0.79 MGLL (0.34) PARLMGLL
SCHEMBL596794 0.78 MAPT (0.44)
SCHEMBL3489296 0.78 TSHR (0.41)
SCHEMBL26978299 0.78 MAPT (0.44)
SCHEMBL3805679 0.77 MGLL (0.33) PARLMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210228530-A1 TAXANE-LIPID-POLYSACCHARIDE DUAL CONJUGATES, PREPARATION METHODS THEREOF AND USES THEREOF SANTOLECAN PHARMACEUTICALS LLC 2021-07-29 US disclosed
US-10016512-B2 Immobilised biological entities CARMEDA AB (SE) 2018-07-10 US disclosed
US-20180140713-A1 IMMOBILISED BIOLOGICAL ENTITIES CARMEDA AB (SE) 2018-05-24 US disclosed
US-20170368237-A1 IMMOBILISED BIOLOGICAL ENTITIES GORE & ASS (US) 2017-12-28 US disclosed
US-20170362624-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS Life Technologies Corporation 2017-12-21 US disclosed
US-9764068-B2 Immobilised biological entities W.L. GORE AND ASSOCIATES INC. (US) 2017-09-19 US disclosed
US-9645140-B2 Labeling and detection of post translationally modified proteins Life Technologies Corporation (US) 2017-05-09 US disclosed
US-20160310646-A1 IMMOBILISED BIOLOGICAL ENTITIES W. L. GORE & ASSOCIATES, INC. 2016-10-27 US disclosed
US-20160228572-A9 Immobilised Biological Entities CARMEDA AB (SE) 2016-08-11 US disclosed
US-9408950-B2 Immobilised biological entities W.L. GORE & ASSOCIATES, INC. (US) 2016-08-09 US disclosed
US-8501212-B2 Immobilised biological entities CARMEDA AB (SE) 2013-08-06 US disclosed
US-20120301894-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS Life Technologies Corporation (US) 2012-11-29 US disclosed
US-20120231043-A1 IMMOBILISED BIOLOGICAL ENTITIES CARMEDA AB (SE) 2012-09-13 US disclosed
US-8114636-B2 Labeling and detection of nucleic acids Life Technologies Corporation (US) 2012-02-14 US disclosed
US-20110223229-A1 IMMOBILISED BIOLOGICAL ENTITIES CARMEDA AB (SE) 2011-09-15 US disclosed
US-20110223229-A1 IMMOBILISED BIOLOGICAL ENTITIES CARMEDA AB (SE) 2011-09-15 US disclosed
US-20100261181-A1 LABELING AND DETECTION OF NUCLEIC ACIDS Life Technologies Corporation (US) 2010-10-14 US disclosed
WO-2009102820-A2 MODIFIED SUGAR SUBSTRATES AND METHODS OF USE GOVERNMENT OF THE U.S A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2009-08-20 WO disclosed
US-20080050731-A1 LABELING AND DETECTION OF NUCLEIC ACIDS INVITROGEN CORPORATION (US) 2008-02-28 US disclosed
US-20070249014-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS INVITROGEN CORPORATION (US) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110223229-A1 IMMOBILISED BIOLOGICAL ENTITIES FGB, SELE, EPCAM PARL 3718/4885MGLL 2325/4885
US-20180140713-A1 IMMOBILISED BIOLOGICAL ENTITIES FGB, SELE, EPCAM PARL 3718/4885MGLL 2325/4885
US-20210228530-A1 TAXANE-LIPID-POLYSACCHARIDE DUAL CONJUGATES, PREPARATION METHODS THEREOF AND USES THEREOF DDOST, UGT2B17, UGT1A7 PARL 4713/4885MGLL 1285/4885
US-10016512-B2 Immobilised biological entities FGB, SELE, EPCAM PARL 3718/4885MGLL 2325/4885
US-20070249014-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS PTMS, DNPEP, BTD PARL 2533/4885MGLL 3813/4885
US-20120231043-A1 IMMOBILISED BIOLOGICAL ENTITIES CD44, CD63, FGB PARL 3624/4885MGLL 2615/4885
US-20160228572-A9 Immobilised Biological Entities FGB, SELE, EPCAM PARL 3718/4885MGLL 2325/4885
US-20170362624-A1 LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS PTMS, DNPEP, BTD PARL 2533/4885MGLL 3813/4885
US-20100261181-A1 LABELING AND DETECTION OF NUCLEIC ACIDS RNGTT, ADAR, ALKBH1 PARL 2659/4885MGLL 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.