Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7553988 | 0.97 | EPHX1 (0.35) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL10724821 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL64468 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL8090124 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL6712839 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| Lithium Ion SCHEMBL1021741 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL3151431 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL5702427 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL1022858 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB | |
| SCHEMBL6712907 | 0.94 | EPHX1 (0.37) | EPHX1HPGDEPHX2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143639-A | Synthesis method of methane bis (benzenesulfonate) | 苏州华道生物药业股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-119098149-A | Adsorbent, preparation method and application | 中国石油化工股份有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-115141134-A | Compound and preparation method and application thereof | 江西同和药业股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| US-10835453-B2 | Storage-stable resin-modified glass ionomer cement | VOCO GMBH (DE) | 2020-11-17 | — | — | US | claimed |
| EP-3338756-B1 | STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT | VOCO GMBH (DE) | 2020-02-26 | — | — | EP | claimed |
| EP-3338756-A1 | STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT | VOCO GmbH (DE) | 2018-06-27 | — | — | EP | claimed |
| US-20180168938-A1 | STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT | VOCO GMBH (DE) | 2018-06-21 | — | — | US | claimed |
| EP-1199303-B1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL CO (JP) | 2004-09-22 | — | — | EP | claimed |
| US-6660888-B2 | A disulfone compound of given formula | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-12-09 | — | — | US | claimed |
| US-20020058844-A1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-16 | — | — | US | claimed |
| EP-1199303-A1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | claimed |
| US-6353041-B1 | PLASTICS FOR SEALING ROOTS OF TEETH | KERR CORPORATION | 2002-03-05 | — | — | US | claimed |
| US-5621084-A | Process for removal of allyl group or allyloxycarbonyl group | PFIZER INC. (US) | 1997-04-15 | — | — | US | claimed |
| EP-0676236-A1 | Process for removal of allyl group or allyloxycarbonyl group | PFIZER INC. (US) | 1995-10-11 | — | — | EP | claimed |
| US-4110270-A | ALKALI METAL SALT OF TOLUENE- OR BENZENE-SULFINIC ACID AS CATALYST | BASF WYANDOTTE CORPORATION (US) | 1978-08-29 | — | — | US | claimed |
| US-4039334-A | ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-02 | — | — | US | claimed |
| JP-9188513-A | — | — | None | — | — | JP | disclosed |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | KURARAY NORITAKE DENTAL INC. (JP) | 2026-05-12 | — | — | US | disclosed |
| US-4110270-A | ALKALI METAL SALT OF TOLUENE- OR BENZENE-SULFINIC ACID AS CATALYST | BASF WYANDOTTE CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4039334-A | ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058844-A1 | Process for producing retinol and intermediate compounds for producing the same | ADH4, ADH1B, ADH7 | EPHX1 676/4885HPGD 364/4885EPHX2 751/4885 |
| US-12622847-B2 | Organosilicon compound and dental composition containing same | MSL1, ITGA1, ITGAL | EPHX1 603/4885HPGD 2116/4885EPHX2 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.