Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336225 | 0.84 | TRPM8 (0.44) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| SCHEMBL6137743 | 0.80 | ALDH1A1 (0.44) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL9474180 | 0.77 | EPHX1 (0.49) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| Bicarbonate SCHEMBL1660906 | 0.76 | EPHX1 (0.47) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| SCHEMBL1659675 | 0.76 | TRPM8 (0.48) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| SCHEMBL19209892 | 0.73 | EPHX1 (0.47) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| Menthol SCHEMBL9645915 | 0.73 | TRPM8 (0.48) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| SCHEMBL1030881 | 0.72 | EPHX1 (0.44) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL4167469 | 0.72 | EPHX1 (0.38) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL31148535 | 0.72 | TRPM8 (0.52) | EPHX1TRPM8TRPA1CYP19A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687311-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | Symrise AG (DE) | 2020-08-05 | — | — | EP | claimed |
| EP-3142499-B1 | HOMOVANILLIC ACID ESTERS, IN PARTICULAR FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | SYMRISE AG (DE) | 2019-10-30 | — | — | EP | claimed |
| WO-2019063069-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | SYMRISE AG (DE) | 2019-04-04 | — | — | WO | claimed |
| EP-3142499-A1 | HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | Symrise AG (DE) | 2017-03-22 | — | — | EP | claimed |
| WO-2015158677-A1 | HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | SYMRISE AG (DE) | 2015-10-22 | — | — | WO | claimed |
| EP-2932858-A1 | Homovanillic acid esters, in particular for achieving an impression of heat and/or spiciness | Symrise AG (DE) | 2015-10-21 | — | — | EP | claimed |
| EP-2008530-B1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | SYMRISE AG (DE) | 2011-01-19 | — | — | EP | claimed |
| EP-2008530-A1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | Symrise GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | claimed |
| US-20240237643-A1 | COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY | SYMRISE AG (DE) | 2024-07-18 | — | — | US | disclosed |
| US-20240216248-A1 | MICROBIAL GLYCOLIPIDS | ANALYTICON DISCOVERY GMBH (DE) | 2024-07-04 | — | — | US | disclosed |
| EP-4393581-A2 | BIODEGRADABLE POLYUREA/POLYURETHANE MICROCAPSULES | Symrise AG (DE) | 2024-07-03 | — | — | EP | disclosed |
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | SYMRISE AG (DE) | 2024-07-02 | — | — | US | disclosed |
| US-12016944-B2 | Mixtures comprising a protein extract for the treatment of human skin and/or hair | SYMRISE AG (DE) | 2024-06-25 | — | — | US | disclosed |
| EP-4378575-A1 | POLYUREA/POLYURETHANE MICROCAPSULES | Symrise AG (DE) | 2024-06-05 | — | — | EP | disclosed |
| EP-1958627-A2 | Use of certain menthyl-3-oxocarbonic acid esters as physiological cooling agents | Symrise GmbH & Co. KG (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1913976-A1 | N-alpha-(menthane carbonyl) amino acid amides and their use as physiological coolants | Symrise GmbH & Co. KG (DE) | 2008-04-23 | — | — | EP | disclosed |
| EP-1765772-A1 | USE OF ALKYLOXYALCANIC ACID AMIDES, IN PARTICULAR IN THE FORM OF AROMATIC SUBSTANCES AND A NOVEL ALKYLOXYALCANIC ACID AMIDE | Symrise GmbH & Co. KG (DE) | 2007-03-28 | — | — | EP | disclosed |
| EP-1682489-A1 | USE OF ALKENE CARBOXLIC ACID N ALKYLAMIDES AS FLAVOURING AGENTS | Symrise GmbH & Co. KG (DE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2006003210-A1 | USE OF ALKYLOXYALCANIC ACID AMIDES, IN PARTICULAR IN THE FORM OF AROMATIC SUBSTANCES AND A NOVEL ALKYLOXYALCANIC ACID AMIDE | SYMRISE GMBH & CO. KG (DE) | 2006-01-12 | — | — | WO | disclosed |
| WO-2005044778-A1 | USE OF ALKENE CARBOXLIC ACID N ALKYLAMIDES AS FLAVOURING AGENTS | SYMRISE GMBH & CO. KG (DE) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12023396-B2 | Flavour and fragrance compositions comprising acetophenone derivatives | FAAH2, ADH5, NISCH | EPHX1 1023/4885TRPM8 678/4885TRPA1 9/4885 |
| US-20240216248-A1 | MICROBIAL GLYCOLIPIDS | UGCG, SGMS1, GPR119 | EPHX1 1409/4885TRPM8 3261/4885TRPA1 1611/4885 |
| US-20240237643-A1 | COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY | ZC3HAV1, SAMHD1, ZC3HAV1L | EPHX1 435/4885TRPM8 2433/4885TRPA1 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.