SCHEMBL1032223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31190571	0.82	ALDH1A1 (0.41)	ALDH1A1HSD17B10TDP1HSD11B1CA1
	SCHEMBL344370	0.78	NPC1 (0.43)	ALDH1A1HSD17B10TDP1HSD11B1LMNA
	SCHEMBL1085985	0.78	HSD11B1 (0.56)	ALDH1A1HSD17B10TDP1HSD11B1KIF11
	SCHEMBL31190709	0.78	ALDH1A1 (0.44)	ALDH1A1HSD17B10TDP1HSD11B1KIF11
	SCHEMBL61336	0.77	KIF11 (0.55)	ALDH1A1HSD17B10TDP1HSD11B1CA1
	Methylene Chloride SCHEMBL3042021	0.76	KIF11 (0.50)	ALDH1A1HSD17B10TDP1HSD11B1CA1
	SCHEMBL17079544	0.74	ALDH1A1 (0.44)	ALDH1A1HSD17B10TDP1HSD11B1KIF11
	SCHEMBL31713594	0.73	ALDH1A1 (0.40)	ALDH1A1HSD17B10TDP1HSD11B1CA1
	SCHEMBL31190811	0.73	ALDH1A1 (0.40)	ALDH1A1HSD17B10TDP1HSD11B1CA1
	SCHEMBL7538033	0.73	KIF11 (0.47)	ALDH1A1HSD17B10TDP1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.