Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP14 | P31944 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449782 | 0.77 | GPR3 (0.39) | CYP1A2CYP2C19GPR3TDP1ATM | |
| SCHEMBL14289090 | 0.75 | LATS1 (0.36) | — | |
| SCHEMBL14289098 | 0.75 | MAPT (0.39) | CYP1A2CYP2C19LMNAHTTMEN1 | |
| SCHEMBL14289093 | 0.75 | CYP1A2 (0.31) | CYP1A2CYP2C19 | |
| SCHEMBL1868846 | 0.71 | GPR3 (0.52) | CYP1A2CYP2C19LMNAHTTGPR3 | |
| SCHEMBL1911314 | 0.71 | CYP1A2 (0.55) | CYP1A2CYP2C19LMNAHTTGPR3 | |
| SCHEMBL803121 | 0.71 | PI4KA (0.50) | CYP1A2LMNAHTTRAB9ATDP1 | |
| SCHEMBL14289099 | 0.71 | HSP90AA1 (0.35) | CYP1A2CYP2C19LMNAHTTKMT2A | |
| SCHEMBL3075819 | 0.70 | LMNA (0.75) | CYP1A2CYP2C19LMNAHTTGPR3 | |
| SCHEMBL179260 | 0.69 | LMNA (0.49) | CYP1A2LMNAHTTGPR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2023-09-12 | — | — | US | disclosed |
| US-9957297-B2 | Template-fixed peptidomimetics as inhibitors of FPR1 | POLYPHOR AG (CH) | 2018-05-01 | — | — | US | disclosed |
| US-9938322-B2 | β-hairpin peptidomimetics | POLYPHOR AG (CH) | 2018-04-10 | — | — | US | disclosed |
| US-20180072774-A1 | BACKBONE-CYCLIZED PEPTIDOMIMETICS WITH GLP-1R MODULATING ACTIVITY | POLYPHOR AG (CH) | 2018-03-15 | — | — | US | disclosed |
| US-20180072775-A1 | Beta-Hairpin Peptidomimetics | POLYPHOR AG (CH) | 2018-03-15 | — | — | US | disclosed |
| US-20180044380-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2018-02-15 | — | — | US | disclosed |
| US-9850284-B2 | Beta-hairpin peptidomimetics | POLYPHOR AG (CH) | 2017-12-26 | — | — | US | disclosed |
| US-20170253634-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2017-09-07 | — | — | US | disclosed |
| US-20170218026-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2017-08-03 | — | — | US | disclosed |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-03-03 | — | — | US | disclosed |
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | POLYPHOR AG (CH) | 2014-09-25 | — | — | US | disclosed |
| US-8217177-B2 | Fused heterocyclic derivatives and methods of use | AMGEN INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20080004273-A1 | Inhibitors of protein tyrosine kinase activity | METHYLGENE, INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004273-A1 | Inhibitors of protein tyrosine kinase activity | METHYLGENE, INC. (CA) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287986-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS AS INHIBITORS OF FPR1 | FPR1, FPR3, FPR2 | CYP1A2 3696/4885CYP2C19 2192/4885LMNA 1842/4885 |
| US-20180044380-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CYP1A2 3983/4885CYP2C19 2664/4885LMNA 2275/4885 |
| US-20180072774-A1 | BACKBONE-CYCLIZED PEPTIDOMIMETICS WITH GLP-1R MODULATING ACTIVITY | GLP1R, GIPR, SSTR1 | CYP1A2 2933/4885CYP2C19 2259/4885LMNA 2624/4885 |
| US-20170253634-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CYP1A2 3983/4885CYP2C19 2664/4885LMNA 2275/4885 |
| US-20170218026-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, BACE1, C1S | CYP1A2 4019/4885CYP2C19 2623/4885LMNA 2311/4885 |
| US-20160060298-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLL, C1S, BACE1 | CYP1A2 3857/4885CYP2C19 2664/4885LMNA 3051/4885 |
| US-20180072775-A1 | Beta-Hairpin Peptidomimetics | POLQ, POLL, POLM | CYP1A2 4770/4885CYP2C19 4091/4885LMNA 1495/4885 |
| US-20080004273-A1 | Inhibitors of protein tyrosine kinase activity | HGF, ERBB2, MET | CYP1A2 4345/4885CYP2C19 4235/4885LMNA 4752/4885 |
| US-11753446-B2 | Beta-hairpin peptidomimetics | POLL, BACE1, C1S | CYP1A2 3983/4885CYP2C19 2664/4885LMNA 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.