SCHEMBL103449

SCHEMBL103449

Nc1nc2cc(F)ccc2s1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 2/20 0.72
AXL P30530 1/20 0.72
PIK3CD O00329 1/20 0.54
PIK3CA P42336 1/20 0.54
PIK3CB P42338 1/20 0.54
PIK3CG P48736 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.50
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
FTO Q9C0B1 1/20 0.50
ILK Q13418 1/20 0.50
DYRK1A Q13627 1/20 0.49
SCN4A P35499 3/20 0.47
EPHX2 P34913 1/20 0.47
RAB9A P51151 3/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29702533 1.00 GFER (0.72) GFERAXLPIK3CDPIK3CAPIK3CB
Hydrochloric Acid SCHEMBL9715291 0.98 AXL (0.70) GFERAXLPIK3CDPIK3CAPIK3CB
SCHEMBL78948 0.84 GFER (1.00) GFERAXLPIK3CDPIK3CAPIK3CB
SCHEMBL2190447 0.79 ALDH1A1 (0.61) GFERAXLPIK3CDPIK3CAPIK3CB
Hydrochloric Acid SCHEMBL11236118 0.78 ALDH1A1 (0.59) GFERAXLPIK3CDPIK3CAPIK3CB
SCHEMBL2432396 0.78 F2RL3 (0.51) GFERAXLSMN1; SMN2ALDH1A1ILK
SCHEMBL12262 0.76 MAPT (0.72) GFERAXLPIK3CDPIK3CAPIK3CB
SCHEMBL21983970 0.76 PIK3CA (0.54) GFERAXLPIK3CDPIK3CAPIK3CB
SCHEMBL72699 0.76 GAA (0.72) GFERAXLPIK3CDPIK3CAPIK3CB
SCHEMBL482340 0.76 LOXL2 (0.61) GFERAXLPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2398771-A2 HETEROCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR Boehringer Ingelheim International GmbH (DE) 2011-12-28 EP claimed
WO-2010096371-A2 HETEROCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-08-26 WO claimed
US-20260144259-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFINYL)BENZO[D]OXAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-28 US disclosed
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-05-28 US disclosed
EP-4748828-A1 METHYLENEBISBIPHENYL COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2026-05-27 EP disclosed
EP-4748826-A1 BIPHENYL COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2026-05-27 EP disclosed
EP-4748827-A1 DIMETHYLPENTA-2-ENEDIOATE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2026-05-27 EP disclosed
EP-4748825-A1 ACRYLIC ACID DERIVATIVE AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2026-05-27 EP disclosed
US-12635692-B2 Method for controlling weeds KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2026-05-26 US disclosed
CN-122029166-A Condensed cyclic compound and harmful arthropod control composition containing the same 住友化学株式会社 2026-05-12 CN disclosed
EP-4737442-A1 DIAMINOVINYLIDENE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAID COMPOUND, AND METHODS FOR USING THESE ADEKA CORPORATION (JP) 2026-05-06 EP disclosed
EP-0588183-A1 Fluoro benzothiazolyloxyacetamide BAYER AG (DE) 1994-03-23 EP disclosed
EP-0533695-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. PFIZER (US) 1993-03-31 EP disclosed
CN-1057839-A The azepine benzoglyoxaline that is used for the treatment of asthma, sacroiliitis and relative disease PFIZER (US) 1992-01-15 CN disclosed
WO-1991017163-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER INC. (US) 1991-11-14 WO disclosed
US-4086241-A Benzothiazolylimidazolidinone esters of furyl and thienyl substituted acids VELSICOL CHEMICAL CORPORATION (US) 1978-04-25 US disclosed
US-4055569-A HERBICIDE VELSICOL CHEMICAL CORPORATION (US) 1977-10-25 US disclosed
US-4054574-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-10-18 US disclosed
US-4045446-A 1-Benzothiazolyl-5-pyridylcarbonyloxyimidazolidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-30 US disclosed
US-4029491-A HERBICIDES VELSICOL CHEMICAL CORPORATION (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144259-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFINYL)BENZO[D]OXAZOLE ATR, CCT4, CRY1 GFER 2908/4885AXL 438/4885PIK3CD 4382/4885
US-20260144258-A1 CRYSTAL OF 2-(5-CYCLOPROPYL-3-(ETHYLSULFONYL)PYRIDIN-2-YL)-5-((TRIFLUOROMETHYL)SULFONYL)BENZO[D]OXAZOLE PDXK, PUM1, CTRL GFER 3715/4885AXL 1783/4885PIK3CD 4374/4885
US-12635692-B2 Method for controlling weeds GYS1, GYS2, ACLY GFER 2549/4885AXL 3286/4885PIK3CD 3588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.