Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743208 | 0.87 | ALDH1A1 (0.30) | FFAR4 | |
| SCHEMBL743209 | 0.84 | METAP2 (0.34) | — | |
| SCHEMBL8758348 | 0.78 | KDM4E (0.38) | — | |
| SCHEMBL9450649 | 0.76 | METAP2 (0.35) | FFAR4 | |
| SCHEMBL2470723 | 0.75 | TSHR (0.40) | — | |
| SCHEMBL271088 | 0.74 | CYP1A2 (0.37) | — | |
| SCHEMBL3341067 | 0.72 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL29118742 | 0.70 | ALDH1A1 (0.47) | — | |
| SCHEMBL29178432 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL8879074 | 0.69 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318176-B1 | Color enhancement for resin blends | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-01-26 | — | — | EP | disclosed |
| EP-1299582-B1 | A PROCESS TO PREPARE MELT-COLORED POLYMERIC FIBERS | SABIC INNOVATIVE PLASTICS IP (NL) | 2008-10-08 | — | — | EP | disclosed |
| EP-0897947-B2 | Fine cell-containing polyester film | MITSUBISHI POLYESTER FILM CORP (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20030146536-A1 | Color enhancement for resin blends | GENERAL ELECTRIC COMPANY | 2003-08-07 | — | — | US | disclosed |
| US-20030129398-A1 | Process to prepare polymeric fibers with improved color and appearance | GENERAL ELECTRIC COMPANY | 2003-07-10 | — | — | US | disclosed |
| EP-1318176-A1 | Color enhancement for resin blends | GENERAL ELECTRIC COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| EP-1299582-A1 | A PROCESS TO PREPARE MELT-COLORED POLYMERIC FIBERS | GENERAL ELECTRIC COMPANY (US) | 2003-04-09 | — | — | EP | disclosed |
| US-6495079-B1 | MELT BLENDING POLYAMIDE OR POLYESTER RESIN, COLORANT AND WATER INSOLUBLE ALKYLENE ARYL POLYESTER SULFONATE SALT COPOLYMER HAVING METAL SULFONATE UNITS, FORMING INTO FILAMENTS, DRAWING INTO FIBERS HAVING IMPROVED COLOR STRENGTH | PRISMA FIBERS, INC. | 2002-12-17 | — | — | US | disclosed |
| EP-0897947-B1 | Fine cell-containing polyester film | MITSUBISHI POLYESTER FILM CORP (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2002000974-A1 | PROCESS TO PREPARE MELT-COLORED POLYMERIC FIBERS | GENERAL ELECTRIC COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| US-6130278-A | GLOSS, PRINTABILITY, TRANSPORT PROPERTY AND/OR FLEXIBILITY; IMAGE-RECEIVING PAPERS SUITABLE FOR VIDEO PRINTER, RELEASE PAPERS | MITSUBISHI POLYSTER FILM CORPORATION (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0897947-A2 | Fine cell-containing polyester film | Mitsubishi Polyester Film Corporation (JP) | 1999-02-24 | — | — | EP | disclosed |
| EP-0159283-B1 | POLYESTER COMPOSITION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0103531-B1 | POLYETHYLENE ISOPHTHALATE HAVING REDUCED CYCLIC DIMER CONTENT AND PROCESS THEREFOR | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| US-4585854-A | Polyester composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0159283-A2 | Polyester composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4525524-A | Polyester composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| EP-0103531-A1 | Polyethylene isophthalate having reduced cyclic dimer content and process therefor | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4418188-A | PROTONIC ACID CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-11-29 | — | — | US | disclosed |
| US-4104262-A | LACQUER BINDING AGENTS | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |