SCHEMBL1043437

SCHEMBL1043437

O=C([O-])CC(Cl)Cl.[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934101 0.77 CA4 (0.52)
SCHEMBL28716378 0.77
SCHEMBL10642815 0.77
Silver SCHEMBL6734699 0.75 CA4 (0.46)
SCHEMBL6734711 0.75 CA4 (0.46)
SCHEMBL27838299 0.75 CA2 (0.46)
SCHEMBL10423091 0.71 CA4 (0.60)
Bicarbonate SCHEMBL7330333 0.71 LMNA (0.39)
Malic Acid SCHEMBL163976 0.71 CA4 (0.94)
Zinc Ion SCHEMBL10512540 0.71 CA2 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118020771-A Chemical emasculation agent and preparation method and application thereof 西南科技大学 2024-05-14 CN claimed
JP-57126402-A None JP disclosed
CN-118020771-A Chemical emasculation agent and preparation method and application thereof 西南科技大学 2024-05-14 CN disclosed
CN-117070404-A Sphingobacterium mucilaginosum ZJPH2023031 and application thereof in preparation of (R) -2-chloropropionic acid 浙江工业大学 2023-11-17 CN disclosed
CN-117070405-A Pseudomonas taiwanensis ZJPH2023032 and application thereof in preparation of (R) -2-chloropropionic acid 浙江工业大学 2023-11-17 CN disclosed
EP-2166014-B1 Method for producing a ruthenium complex TAKASAGO PERFUMERY CO LTD (JP) 2012-11-14 EP disclosed
US-7964744-B2 Method for producing a ruthenium complex TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-06-21 US disclosed
EP-2275429-A2 Method for producing a ruthenium complex Takasago International Corporation (JP) 2011-01-19 EP disclosed
US-20100076210-A1 METHOD FOR PRODUCING A RUTHENIUM COMPLEX TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-03-25 US disclosed
EP-2166014-A2 Method for producing a ruthenium complex Takasago International Corporation (JP) 2010-03-24 EP disclosed
WO-1993017971-A1 MATERIALS AND METHODS FOR ENHANCED PHOTOCATALYZATION OF ORGANIC COMPOUNDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-09-16 WO disclosed
JP-S57126402-A GRANULAR PROLONGED RELEASE TYPE AGRICULTURAL CHEMICAL ASAHI CHEM IND CO LTD 1982-08-06 JP disclosed
US-4294845-A ANTILIPEMIC AGENTS ROUSSEL UCLAF, A CORP. OF FRANCE (FR) 1981-10-13 US disclosed