Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | INMT | O95050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809711 | 0.95 | NOS1 (0.46) | NOS1NOS2ACHEALPLALPI | |
| SCHEMBL10377977 | 0.85 | ALPL (0.50) | NOS1NOS2ACHEALPLALPI | |
| SCHEMBL10376372 | 0.80 | ALPL (0.51) | NOS1NOS2ACHEALPLALPI | |
| SCHEMBL8864841 | 0.70 | ACHE (0.52) | ACHEADRA2BKCNH2CYP2D6TSHR | |
| SCHEMBL14777372 | 0.68 | INMT (0.48) | NOS1NOS2ACHEUSP2INMT | |
| SCHEMBL20829048 | 0.68 | ALDH1A1 (0.38) | ACHECYP1A2TSHRALOX12ALDH1A1 | |
| SCHEMBL14614913 | 0.68 | KEAP1 (0.40) | NOS1NOS2ACHECYP1A2TSHR | |
| SCHEMBL21400809 | 0.66 | METAP2 (0.35) | ACHETSHRMAPK1ALDH1A1LMNA | |
| SCHEMBL7876143 | 0.66 | ALPL (0.47) | ALPLALPIADRA2BDRD1KCNH2 | |
| SCHEMBL10376431 | 0.66 | SCN1A (0.40) | NOS1NOS2ACHETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247692-B1 | ELASTOMERIC FLUID COMPOSITIONS, CROSSLINKING IN THE PRESENCE OF AMBIENT HUMIDITY, SUITABLE FOR USE IN SEALANTS | ENICHEM SYNTHESIS S.p.A. (IT) | 1990-07-18 | — | — | EP | claimed |
| US-4757116-A | Elastomeric aliphatic polycarbonate, bisketimine, bisketiminoenamine, or bisketiminosilazane organic compound, cyclic amidine compound | ENICHEM SINTESI S.P.A. (IT) | 1988-07-12 | — | — | US | claimed |
| EP-0247692-B1 | ELASTOMERIC FLUID COMPOSITIONS, CROSSLINKING IN THE PRESENCE OF AMBIENT HUMIDITY, SUITABLE FOR USE IN SEALANTS | ENICHEM SYNTHESIS S.p.A. (IT) | 1990-07-18 | — | — | EP | disclosed |
| EP-0247692-A2 | Elastomeric fluid compositions, crosslinking in the presence of ambient humidity, suitable for use in sealants | ENICHEM SYNTHESIS S.p.A. (IT) | 1987-12-02 | — | — | EP | disclosed |