Sugi Predict

Sugi Predict / Compounds / SCHEMBL1046232

SCHEMBL1046232

SCHEMBL1046232

OCc1c(Br)cccc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRA1 P14867 2/20 0.42
▸ GABRG2 P18507 1/20 0.42
▸ GABRB3 P28472 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.36
▸ DRD4 P21917 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ GAA P10253 1/20 0.32
▸ TAAR1 Q96RJ0 1/20 0.32
▸ CA2 P00918 2/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA7 P43166 1/20 0.31
▸ CA9 Q16790 1/20 0.31
▸ IDO1 P14902 2/20 0.31
▸ PLCG1 P19174 1/20 0.31
▸ CA4 P22748 1/20 0.31
▸ AHR P35869 1/20 0.31
▸ GABRB2 P47870 1/20 0.31
▸ GRM2 Q14416 1/20 0.31
▸ ENPP2 Q13822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1232142 0.85 APOBEC3G (0.38) GABRA1GABRG2GABRB3ALDH1A1DRD4
SCHEMBL15065955 0.85 CA2 (0.38) GABRA1GABRG2GABRB3ALDH1A1DRD4
SCHEMBL29790993 0.85 APOBEC3G (0.38) GABRA1GABRG2GABRB3ALDH1A1DRD4
SCHEMBL30173566 0.83 TAAR1 (0.41) GABRA1GABRG2GABRB3ALDH1A1GAA
SCHEMBL17103694 0.83 GABRA1 (0.40) GABRA1GABRG2GABRB3ALDH1A1DRD4
SCHEMBL606472 0.83 ALDH1A1 (0.48) GABRA1GABRG2GABRB3ALDH1A1TSHR
SCHEMBL15569427 0.83 AKR1B1 (0.43) GABRA1GABRG2GABRB3ALDH1A1MAPK1
SCHEMBL29960244 0.83 AKR1B1 (0.43) GABRA1GABRG2GABRB3ALDH1A1MAPK1
SCHEMBL1372190 0.83 GABRA1 (0.35) GABRA1GABRG2GABRB3ALDH1A1TSHR
SCHEMBL2063479 0.83 TAAR1 (0.41) GABRA1GABRG2GABRB3ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108017522-B Preparation process of 2, 6-dibromobenzene methane sulfonyl chloride 贵州大学 2021-01-05 — — CN claimed
US-12590062-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2026-03-31 — — US disclosed
US-20250368620-A1 ARNT Degrading Compounds and Uses Thereof CELGENE CORPORATION (US) 2025-12-04 — — US disclosed
WO-2025077770-A1 FUSED RING COMPOUND AND USE THEREOF IN KRAS INHIBITOR 成都海博为药业有限公司 2025-04-17 — — WO disclosed
WO-2025077663-A1 FUSED RING COMPOUND AND USE 成都海博为药业有限公司 2025-04-17 — — WO disclosed
CN-118878461-A PD-1/PD-L1 inhibitors 吉利德科学公司 2024-11-01 — — CN disclosed
CN-118851958-A Acyl sulfonamide compound, preparation method and application thereof 中国医学科学院药物研究所 2024-10-29 — — CN disclosed
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2024-04-30 — — US disclosed
CN-117820333-A KRAS G12C inhibitors 伊莱利利公司 2024-04-05 — — CN disclosed
CN-111138301-B Biphenyl compound, intermediate, preparation method, pharmaceutical composition and application 上海再极医药科技有限公司 2024-01-05 — — CN disclosed
US-20140161729-A1 COFLUORONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2014-06-12 — — US disclosed
EP-2694707-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME Cornell University (US) 2014-02-12 — — EP disclosed
WO-2013058824-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2013-04-25 — — WO disclosed
WO-2012154213-A1 COFLUORONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2012-11-15 — — WO disclosed
EP-2269694-A2 Antituberculous composition comprising oxazole compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2011-01-05 — — EP disclosed
US-20090275528-A1 ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-11-05 — — US disclosed
EP-1931425-A1 ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-06-18 — — EP disclosed
WO-2007043542-A9 ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS OTSUKA PHARMA CO LTD (JP) 2008-05-08 — — WO disclosed
WO-2007043542-A1 ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-04-19 — — WO disclosed
US-4060468-A TUNGSTEN CONTAINING THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-11-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CALCOCO2, MDN1, MBNL1 GABRA1 2394/4885GABRG2 1456/4885GABRB3 2596/4885
US-20090275528-A1 ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS OXA1L, ARG1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 GABRA1 2436/4885GABRG2 3879/4885GABRB3 3193/4885
US-12590062-B2 PD-1/PD-L1 inhibitors CD274, PDCD1LG2, PDCD1 GABRA1 192/4885GABRG2 373/4885GABRB3 160/4885
US-20140161729-A1 COFLUORONS AND METHODS OF MAKING AND USING THEM TNFSF11, CD14, TNFRSF1A GABRA1 806/4885GABRG2 1287/4885GABRB3 1325/4885
US-20250368620-A1 ARNT Degrading Compounds and Uses Thereof ARNT, AHR, NR1H2 GABRA1 2314/4885GABRG2 2423/4885GABRB3 2264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.