SCHEMBL105104

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL103488	0.94	HSD11B1 (0.39)	HSD11B1TDP1TSHRSMN1; SMN2HTR6
	SCHEMBL108682	0.92	TBXA2R (0.41)	HSD11B1TDP1TSHRSMN1; SMN2L3MBTL1
	SCHEMBL14716886	0.89	TDP1 (0.37)	HSD11B1TDP1TSHRL3MBTL1ALDH1A1
	SCHEMBL107169	0.88	CES2 (0.43)	HSD11B1SMN1; SMN2L3MBTL1PSIP1ALDH1A1
	SCHEMBL105771	0.87	CA1 (0.40)	HSD11B1TDP1TSHRSMN1; SMN2HTR6
	SCHEMBL106460	0.85	MEN1 (0.50)	HSD11B1TDP1TSHRL3MBTL1ALDH1A1
	SCHEMBL105635	0.84	CES2 (0.47)	KDM4E
	SCHEMBL104394	0.83	HSD11B1 (0.47)	HSD11B1TSHRSMN1; SMN2L3MBTL1PSIP1
	SCHEMBL106472	0.83	ALDH1A1 (0.42)	HSD11B1TDP1TSHRSMN1; SMN2HTR6
	SCHEMBL107321	0.82	CES2 (0.49)	KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.