SCHEMBL1059080

SCHEMBL1059080

C=CC(N)(C(=O)CN)C(=O)CN

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8935122 0.69 LMNA (0.37) ALDH1A1TSHRFGFR4
SCHEMBL9573116 0.67 ALDH1A1 (0.40) ALDH1A1TSHRFGFR4
SCHEMBL801097 0.63 GLRA1 (0.37) GLRA1SLC6A9OR51E2
SCHEMBL9642490 0.63
SCHEMBL7205332 0.63 GLRA1 (0.37) GLRA1SLC6A9OR51E2
SCHEMBL7864319 0.61 GLRA1 (0.42) GLRA1SLC6A9OR51E2ALDH1A1
Vinyl Ether SCHEMBL5600513 0.59 GLRA1 (0.56) GLRA1SLC6A9OR51E2ALDH1A1TSHR
SCHEMBL451714 0.59
SCHEMBL1843588 0.59
SCHEMBL4953695 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3141615-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2019-10-23 EP disclosed
US-20190048401-A1 OPTIMIZED REAL-TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2019-02-14 US disclosed
EP-1348713-B1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES INC (US) 2019-01-23 EP disclosed
US-10144957-B2 Optimized real time nucleic acid detection processes ENZO LIFE SCIENCES, INC. (US) 2018-12-04 US disclosed
US-10144956-B2 Processes for quantitative or qualitative detection of single-stranded or double-stranded nucleic acids ENZO BIOCHEM, INC. (US) 2018-12-04 US disclosed
EP-2366798-B1 Nucleic acid detection process involving energy transfer labels on nucleotide ENZO LIFE SCIENCES INC (US) 2017-06-28 EP disclosed
EP-1344835-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2017-06-14 EP disclosed
EP-3141615-A1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS Enzo Life Sciences, Inc. (US) 2017-03-15 EP disclosed
US-20160281146-A1 OPTIMIZED REAL TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2016-09-29 US disclosed
US-20160273028-A1 PROCESSES FOR QUANTITATIVE OR QUALITATIVE DETECTION OF SINGLE-STRANDED OR DOUBLE-STRANDED NUCLEIC ACIDS ENZO LIFE SCIENCES, INC. (US) 2016-09-22 US disclosed
US-20050004350-A1 Novel chemiluminescent reagents ENZO LIFE SCIENCES, INC. (US) 2005-01-06 US disclosed
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes ENZO LIFE SCIENCES, INC. 2004-12-16 US disclosed
US-20040229248-A1 Novel dye labeling composition ENZO LIFE SCIENCES, INC. 2004-11-18 US disclosed
US-20040230036-A1 Heterodimeric dye composition ENZO LIFE SCIENCES, INC. (US) 2004-11-18 US disclosed
US-20040203038-A1 Process for preparing novel cyanine dye labeling reagents ENZO LIFE SCIENCES, INC. 2004-10-14 US disclosed
US-20040192893-A1 comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics ENZO LIFE SCIENCES, INC. (US) 2004-09-30 US disclosed
US-20040176586-A1 Process for detecting the presence or quantity of enzymatic activity in a sample ENZO LIFE SCIENCES, INC. (US) 2004-09-09 US disclosed
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES, INC. 2003-12-04 US disclosed
EP-1348713-A2 Labeling reagents and labeled tabeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses Enzo Life Sciences, Inc. (US) 2003-10-01 EP disclosed
EP-1344835-A2 Real-time nucleic acid detection processes and compositions Enzo Life Sciences, Inc. (US) 2003-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229248-A1 Novel dye labeling composition IK, PHAX, CHLSN GLRA1 4156/4885SLC6A9 4731/4885OR51E2 2682/4885
US-20040203038-A1 Process for preparing novel cyanine dye labeling reagents PHAX, IK, CHLSN GLRA1 4264/4885SLC6A9 4692/4885OR51E2 3174/4885
US-20050004350-A1 Novel chemiluminescent reagents CHLSN, CYBA, HLCS GLRA1 4155/4885SLC6A9 4817/4885OR51E2 2271/4885
US-20040176586-A1 Process for detecting the presence or quantity of enzymatic activity in a sample RNGTT, POLRMT, CHLSN GLRA1 4552/4885SLC6A9 4709/4885OR51E2 3158/4885
US-20040230036-A1 Heterodimeric dye composition IK, CHLSN, CRY2 GLRA1 3440/4885SLC6A9 4556/4885OR51E2 2355/4885
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses POLRMT, CHLSN, PHAX GLRA1 3865/4885SLC6A9 4543/4885OR51E2 2255/4885
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes IK, RBM25, CHLSN GLRA1 2615/4885SLC6A9 4774/4885OR51E2 1588/4885
US-20040192893-A1 comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics CHLSN, DDB1, PROC GLRA1 4308/4885SLC6A9 4620/4885OR51E2 3364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.