Benzylamine

Benzylamine

SCHEMBL1061904

NCc1ccccc1.O=[PH](O)O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 5/20 0.70
TSHR P16473 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
TAAR1 Q96RJ0 2/20 0.52
ENPP2 Q13822 1/20 0.48
MAOB P27338 1/20 0.45
CYP2A6 P11509 1/20 0.44
HTR2A P28223 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ABAT P80404 1/20 0.44
F10 P00742 1/20 0.43
PNMT P11086 1/20 0.43
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
AKR1B1 P15121 1/20 0.42
HTR6 P50406 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylamine SCHEMBL1766058 1.00 LOXL2 (0.70) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL27699388 0.87 LOXL2 (0.82) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL283107 0.87 LOXL2 (0.58) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL27781209 0.87 LOXL2 (0.93) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL2841167 0.84 LOXL2 (0.78) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL2841170 0.84 LOXL2 (0.78) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL1331207 0.84
Benzylamine SCHEMBL5481672 0.84 LOXL2 (1.00) LOXL2TSHRCYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL373 0.84
Benzylamine SCHEMBL10707644 0.84 LOXL2 (1.00) LOXL2TSHRCYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2383264-B1 EPOXY COMPOUND PRODUCTION METHOD SHOWA DENKO KK (JP) 2015-03-04 EP disclosed
US-8536352-B2 Method of producing epoxy compounds SHOWA DENKO K.K. (JP) 2013-09-17 US disclosed
CN-101724599-B Use of dendrimers to stimulate cell growth CENTRE NAT RECH SCIENT 2013-08-14 CN disclosed
US-8466303-B2 Process for production of epoxy compound SHOWA DENKO K.K. (JP) 2013-06-18 US disclosed
CN-101031638-B Use of dendrimers to stimulate cell growth CENTRE NAT RECH SCIENT 2012-09-19 CN disclosed
EP-2383264-A1 EPOXY COMPOUND PRODUCTION METHOD Showa Denko K.K. (JP) 2011-11-02 EP disclosed
US-20110263882-A1 METHOD OF PRODUCING EPOXY COMPOUNDS SHOWA DENKO K.K. (JP) 2011-10-27 US disclosed
US-20110009652-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND SHOWA DENKO KK (JP) 2011-01-13 US disclosed
EP-2261219-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND Showa Denko K.K. (JP) 2010-12-15 EP disclosed
CN-101724599-A Use of dendrimers to stimulate cell growth CENTRE NAT RECH SCIENT 2010-06-09 CN disclosed
CN-101031638-A Use of dendrimers to stimulate cell growth INST NAT SANTE RECH MED (FR) 2007-09-05 CN disclosed
US-20070111126-A1 Epoxidized low-molecular-weight ethylene polymer, release agent for electrophotographic toner, and electrophotographic toner for developing electrostatic charge image MITSUI CHEMICALS, INC. (JP) 2007-05-17 US disclosed
EP-1707579-A1 EPOXIDIZED LOW-MOLECULAR-WEIGHT ETHYLENE POLYMER, MOLD-RELEASING AGENT FOR ELECTROPHOTOGRAPHIC TONER, AND ELECTROPHOTOGRAPHIC TONER FOR DEVELOPING ELECTROSTATIC IMAGE Mitsui Chemicals, Inc. (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263882-A1 METHOD OF PRODUCING EPOXY COMPOUNDS AOX1, NOX4, AOC2 LOXL2 1134/4885TSHR 3414/4885CYP1A2 281/4885
US-20110009652-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND DUOX2, EPX, DUOX1 LOXL2 339/4885TSHR 4326/4885CYP1A2 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.