Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695891 | 0.87 | OPRD1 (0.41) | NR3C1ARESR2 | |
| SCHEMBL10693883 | 0.86 | BACE1 (0.44) | NR3C1ARBACE1LMNAHTT | |
| SCHEMBL10692682 | 0.83 | NPC1 (0.47) | EHMT2NR3C1ARPKMBACE1 | |
| SCHEMBL10692592 | 0.78 | BACE1 (0.44) | ARBACE1 | |
| SCHEMBL10695992 | 0.76 | SCN9A (0.39) | ARLMNAL3MBTL1HTR7 | |
| SCHEMBL10691351 | 0.73 | GPR55 (0.39) | CNR1GPR55EHMT2PKMESR2 | |
| SCHEMBL10694576 | 0.73 | POLB (0.33) | PKMBACE1LMNAHTTHTR7 | |
| SCHEMBL10694392 | 0.71 | NPC1 (0.47) | CNR1GPR55EHMT2PKMLMNA | |
| SCHEMBL20714380 | 0.71 | L3MBTL1 (0.41) | EHMT2BACE1LMNAHTTNPSR1 | |
| SCHEMBL20710608 | 0.68 | ALDH1A1 (0.57) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0212216-A1 | Dihydroquinolinone derivatives, processes for their preparation, medicaments containing them, the use of these medicaments, and intermediates for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |