Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693674 | 0.89 | BACE1 (0.35) | BACE1BACE2ALDH1A1TSHRLMNA | |
| SCHEMBL10692186 | 0.86 | BACE1 (0.35) | BACE1BACE2ALDH1A1MAPTLMNA | |
| SCHEMBL10691593 | 0.83 | L3MBTL1 (0.42) | BACE1BACE2ALDH1A1TSHRMAPT | |
| SCHEMBL10694665 | 0.83 | RAD52 (0.36) | ALDH1A1TSHRMAPTLMNAHTT | |
| SCHEMBL10696619 | 0.79 | RAD52 (0.34) | ALDH1A1MAPTHTTPOLBSLC6A2 | |
| SCHEMBL10691351 | 0.78 | GPR55 (0.39) | ALDH1A1TSHRMAPTLMNAHPGD | |
| SCHEMBL10674089 | 0.77 | BACE1 (0.37) | BACE1BACE2ALDH1A1TSHRMAPT | |
| SCHEMBL10693819 | 0.71 | OPRD1 (0.40) | EHMT2 | |
| SCHEMBL10675808 | 0.70 | BACE1 (0.38) | BACE1BACE2ALDH1A1TSHRMAPT | |
| SCHEMBL10691597 | 0.69 | ADRA1A (0.39) | ALDH1A1TSHRMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |