Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694802 | 0.87 | BACE1 (0.44) | BACE1BACE2ALDH1A1KMT2ATSHR | |
| SCHEMBL10691351 | 0.85 | GPR55 (0.39) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL10692789 | 0.83 | BACE1 (0.37) | BACE1BACE2ALDH1A1TSHRPOLB | |
| SCHEMBL10691597 | 0.80 | ADRA1A (0.39) | L3MBTL1ADAMTS5ALDH1A1TSHRSCN9A | |
| SCHEMBL10693819 | 0.77 | OPRD1 (0.40) | — | |
| SCHEMBL10693883 | 0.75 | BACE1 (0.44) | L3MBTL1BACE1BACE2ADAMTS5ALDH1A1 | |
| SCHEMBL10695401 | 0.74 | RAD52 (0.42) | BACE1ADAMTS5ALDH1A1TSHRMAPT | |
| SCHEMBL10693674 | 0.74 | BACE1 (0.35) | L3MBTL1BACE1BACE2ALDH1A1TSHR | |
| SCHEMBL10694665 | 0.69 | RAD52 (0.36) | ALDH1A1TSHRPOLBMAPTPKM | |
| SCHEMBL16155483 | 0.69 | ADAMTS5 (0.51) | L3MBTL1BACE1BACE2ADAMTS5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778793-A | CONTROLLING CALCIUM CONCENTRATION-CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |